Anti-Phospho-Ser499 FMRP (Fragile X Mental Retardation Protein)

• Catalog number
  MBS502189
• Price
  Please ask
• Size
  0.1 mL

• Products_type
  Antibody
• Products_short_name
  [FMRP (Ser499)]
• Other_names
  [fragile X mental retardation protein 1 homolog; Fragile X mental retardation protein 1 homolog; fragile X mental retardation protein 1 homolog; protein FMR-1; fragile X mental retardation-1 protein; fragile X mental retardation syndrome 1 homolog; fragile X mental retardation 1]
• Products_gene_name
  [FMR1]
• Other_gene_names
  [Fmr1; Fmr1; FMRP; FMRP]
• Clonality
  Polyclonal
• Specificity
  Specific for ~71k FMRP protein phosphorylated at Ser499. Immunolabeling of the FMRP protein is completely eliminated by lambda-phosphatase.
• Purity
  Affinity Purified
• Form
  100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots
• Storage_stability
  For long term storage -80°C is recommended, but shorter term storage at -20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stock solutions are stable for a minimum of 1 year at -20°C.
• Tested_application
  Western Blot (WB) and Dot blots (DB). Immunohistochemistry (IHC) has not yet been determined.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

• Gene target
  Phospho-Ser499   FMRP   Fragile   Mental   Retardation   Protein  
• Gene symbol
  FMR1
• Short name
  Anti-Phospho-Ser499 FMRP (Fragile X Mental Retardation Protein)
• Technique
  anti-, anti, antibody to, antibodies
• Host
  Rabbit
• Alternative name
  Antibody tophosphorilated-Ser499 FMRP (Fragile X Mental Retardation Protein)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3775
• Gene
  FMR1
• Long gene name
  FMRP translational regulator 1
• Synonyms gene
  • POF1
  • POF
• Synonyms gene name
  • premature ovarian failure 1
  • fragile X mental retardation 1
• Synonyms
  • FMRP
  • FRAXA
  • MGC87458
• GenBank acession
  • X69962
• Locus
  Xq27.3
• Discovery year
  1992-01-17
• Entrez gene record
  2332
• Pubmed identfication
  • 1572655
• RefSeq identity
  • NM_002024
• VEGA ID
  OTTHUMG00000022606
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_762

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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