Anti-PD-1 (pembrolizumAbbiosimilar) mAb

Products_type

Antibody
Products_short_name

[PD-1]
Products_name_syn

[MK-3475; PDCD1; PD1; CD279; SLEB2]
Other_names

[Programmed cell death protein 1; Programmed cell death protein 1; programmed cell death protein 1; programmed cell death 1; CD_antigen: CD279]
Products_gene_name

[PD-1]
Other_gene_names

[PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1]
Clonality

Monoclonal
Reactivity

Human
Specificity

Human
Purity

Purified from cell culture supernatant by affinity chromatography
Form

Liquid; 0.1% Procline 300; 50% Glycerol; PBS, pH7.4; 0.1% BSA
Storage_stability

Store at -20 degree C (Avoid repeated freezing and thawing) Shipping: Blue Ice
Tested_application

ELISA (EIA), Flow Cytometry (FC/FACS)
Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

Gene target

PD-1 pembrolizumAbbiosimilar mAb
Gene symbol

PDCD1, ENPP2, SPATA2, SNCA, ENPP3, PDCD1LG2, CD274, IGHVII-1-1, MIR1-1, TRUND-NNN8-1
Short name

Anti-PD-1 (pembrolizumAbbiosimilar) mAb
Technique

anti-, anti, antibody to, antibodies
Host

Human
Isotype

IgG4
Alternative name

Antibody toPD-1 (pembrolizumAbbiosimilar) monoclonal
Alternative technique

antibodies

Identity

HGNC:11138
Gene

SNCA
Long gene name

synuclein alpha
Synonyms gene
- PARK1
- PARK4
Synonyms gene name
- Parkinson disease (autosomal dominant, Lewy body) 4
- synuclein, alpha (non A4 component of amyloid precursor)
Synonyms
- NACP
- PD1
Synonyms name
GenBank acession
- L08850
Locus

4q22.1
Discovery year

1995-01-24
Entrez gene record

6622
Pubmed identfication
- 8248242
- 14593171
VEGA ID

OTTHUMG00000130948
Locus Specific Databases
- Global Variome shared LOVD

Identity

HGNC:3358
Gene

ENPP3
Long gene name

ectonucleotide pyrophosphatase/phosphodiesterase 3
Synonyms gene
- PDNP3
Synonyms
- PD-IBETA
- gp130RB13-6
- B10
- CD203c
GenBank acession
- AF005632
Locus

6q23.2
Discovery year

1995-08-10
Entrez gene record

5169
Pubmed identfication
- 9344668
Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
- CD molecules
VEGA ID

OTTHUMG00000016292

Identity

HGNC:18731
Gene

PDCD1LG2
Long gene name

programmed cell death 1 ligand 2
Synonyms
- PD-L2
- Btdc
- PDL2
- bA574F11.2
- CD273
- B7-DC
Synonyms name
- B7 dendritic cell molecule
GenBank acession
- AF344424
Locus

9p24.1
Discovery year

2003-11-14
Entrez gene record

80380
Pubmed identfication
- 11224527
RefSeq identity
- NM_025239
Classification
- B7 family
- CD molecules
- Immunoglobulin like domain containing
- Receptor ligands
VEGA ID

OTTHUMG00000019504

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data