Anti - Orexin 2 Receptor (Hypocretin 2 Receptor)

• Catalog number
  MBS620057
• Price
  Please ask
• Size
  5x0.1 mL

• Products_type
  Antibody
• Products_short_name
  [Orexin 2 Receptor]
• Products_name_syn
  [Orexin 2 Receptor (Hypocretin 2 Receptor)]
• Other_names
  [orexin receptor type 2; Orexin receptor type 2; orexin receptor type 2; ox2-R; ox-2-R; OTTHUMP00000017762; hypocretin receptor type 2; hypocretin (orexin) receptor 2; Hypocretin receptor type 2]
• Other_gene_names
  [HCRTR2; HCRTR2; OX2R]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Rat is 90% homologous with human OX2R. human OX2R22 immunogenic peptide is 89% homologous with the rat OX2 receptor. However, no significant homology is seen with OX1R or other G-protein-coupled receptors. Antibody reactivity in all species is not established. Control peptide, because of its low MW (
• Purity
  Serum
• Form
  Serum Supplied as a liquid, neat serum, 40% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA, Western Blot
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Orexin   Receptor   Hypocretin   Receptor  
• Gene symbol
  HCRTR2
• Short name
  Anti - Orexin 2 Receptor (Hypocretin 2 Receptor)
• Technique
  anti, antibody to
• Host
  Host: Rabbit Source: Human
• Isotype
  IgG
• Alternative name
  antibody to - Orexin 2 Receptor (Hypocretin 2 Receptor)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4849
• Gene
  HCRTR2
• Long gene name
  hypocretin receptor 2
• Synonyms gene name
  • hypocretin (orexin) receptor 2
• Synonyms
  • OX2R
  • OXR2
  • ORXR2
• Synonyms name
  • orexin receptor 2
• GenBank acession
  • AF041245
• Locus
  6p12.1
• Discovery year
  1998-04-21
• Entrez gene record
  3062
• Pubmed identfication
  • 9491897
• Classification
  • Hypocretin receptors
• VEGA ID
  OTTHUMG00000016150

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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