Anti-Lymphotoxin alpha [3F12.2D3]
-
Catalog number
MBS488356
-
Price
Please ask
-
Size
0.2 mg
-
-
Products_type
Recombinant Antibody
-
Products_short_name
[Lymphotoxin alpha]
-
Products_name_syn
[chimeric 3F12; LT; LTalpha3; Tumor necrosis factor beta; Tumor necrosis factor beta; Tumor necrosis factor-beta; tumor necrosis factor-beta; TNF beta; TNF-beta; TNF beta; TNF-beta; Lymphotoxin-alpha; Lymphotoxin alpha]
-
Other_names
[lymphotoxin-alpha; Lymphotoxin-alpha; lymphotoxin-alpha; lymphotoxin alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1]
-
Products_gene_name
[LTalpha]
-
Other_gene_names
[LTA; LTA; LT; TNFB; TNFSF1; TNLG1E; TNFB; TNFSF1; LT-alpha]
-
Clonality
Monoclonal
-
Clone
[3F12.2D3]
-
Reactivity
Human
-
Specificity
3F12 binds to human LTalpha3 and LTalphabeta (with a KD of ~0.3 nM, determined by BIACORE; ~ 37 pM, determined by ELISA) in both its soluble homotrimeric and membrane heterotrimeric forms. LTalpha belongs to the tumor necrosis factor (TNF) superfamily and is secreted as a homo-trimer (LTalpha3), or is expressed on the cell surface in complex with LTbeta. Lymphotoxin is produced by lymphocytes and in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. LTalpha3 signaling induces target cells to upregulate many chemokines and cytokines in an NFkB-dependent manner.
-
Purity
Protein A Affinity Purified
-
Concentration
1 mg/ml
-
Storage_stability
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
-
Tested_application
Neutralization, ELISA (EIA), Flow Cytometry (FC/FACS), Surface Plasmon Resonance (SPR)
-
Description
The Anti-Lymphotoxin alpha [3F12 2D3] is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Gene target
-
Short name
Anti-Lymphotoxin alpha [3F12 2D3]
-
Technique
anti-, anti, antibody to, antibodies
-
Isotype
Mouse IgG2b, Kappa
-
Alternative name
Antibody toLymphotoxin a [3F12.2D3]
-
Alternative technique
antibodies
-
MeSH Data
-
Name
-
Concept
Scope note:
Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels.
-
Tree numbers
- E05.196.401.250
- E05.301.300.230
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products