Anti-Lymphotoxin alpha [3F12.2D3]

• Catalog number
  MBS488355
• Price
  Please ask
• Size
  0.2 mg

• Products_type
  Recombinant Antibody
• Products_short_name
  [Lymphotoxin alpha]
• Products_name_syn
  [chimeric 3F12; LT; LTalpha3; Tumor necrosis factor beta; Tumor necrosis factor beta; Tumor necrosis factor-beta; tumor necrosis factor-beta; TNF beta; TNF-beta; TNF beta; TNF-beta; Lymphotoxin-alpha; Lymphotoxin alpha]
• Other_names
  [lymphotoxin-alpha; Lymphotoxin-alpha; lymphotoxin-alpha; lymphotoxin alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1]
• Products_gene_name
  [LTalpha]
• Other_gene_names
  [LTA; LTA; LT; TNFB; TNFSF1; TNLG1E; TNFB; TNFSF1; LT-alpha]
• Clonality
  Monoclonal
• Clone
  [3F12.2D3]
• Reactivity
  Human
• Specificity
  3F12 binds to human LTalpha3 and LTalphabeta (with a KD of ~0.3 nM, determined by BIACORE; ~ 37 pM, determined by ELISA) in both its soluble homotrimeric and membrane heterotrimeric forms. LTalpha belongs to the tumor necrosis factor (TNF) superfamily and is secreted as a homo-trimer (LTalpha3), or is expressed on the cell surface in complex with LTbeta. Lymphotoxin is produced by lymphocytes and in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. LTalpha3 signaling induces target cells to upregulate many chemokines and cytokines in an NFkB-dependent manner.
• Purity
  Protein A Affinity Purified
• Concentration
  1 mg/ml
• Storage_stability
  Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
• Tested_application
  Neutralization, ELISA (EIA), Flow Cytometry (FC/FACS), Surface Plasmon Resonance (SPR)
• Description
  The Anti-Lymphotoxin alpha [3F12 2D3] is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

• Gene target
  Lymphotoxin   alpha   [3F12   2D3]  
• Short name
  Anti-Lymphotoxin alpha [3F12 2D3]
• Technique
  anti-, anti, antibody to, antibodies
• Isotype
  Rabbit IgG, Kappa
• Alternative name
  Antibody toLymphotoxin a [3F12.2D3]
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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