-
Products_type
Recombinant Antibody
-
Products_short_name
[Muscle Acetylcholine Receptor]
-
Products_name_syn
[AChR]
-
Other_names
[acetylcholine receptor subunit alpha isoform b; Acetylcholine receptor subunit alpha; acetylcholine receptor subunit alpha; cholinergic receptor nicotinic alpha 1 subunit]
-
Products_gene_name
[AChR]
-
Other_gene_names
[CHRNA1; CHRNA1; ACHRA; ACHRD; CHRNA; CMS1A; CMS1B; CMS2A; FCCMS; SCCMS; ACHRA; CHNRA]
-
Clonality
Monoclonal
-
Clone
[mAb 192]
-
Reactivity
Human, Mouse, Rat
-
Specificity
The antibody binds to human muscle AChR with a Kd of 10 pM, to mouse muscle AChR with a Kd of 50 pM, and to rat muscle AChR with a Kd of 646 nM.
-
Purity
Protein A Affinity Purified
-
Form
PBS only with 0.02% Proclin 300.
-
Concentration
1 mg/ml
-
Storage_stability
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
-
Tested_application
ELISA (EIA), Western Blot (WB), Blocking (BL)
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Test
MyBioSource supplies antibodies that are for research of human proteins.
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.