Anti-Fas [R-125224]

• Catalog number
  MBS488361
• Price
  Please ask
• Size
  0.2 mg

• Products_type
  Recombinant Antibody
• Products_short_name
  [Fas]
• Products_name_syn
  [h-HFE7A; Tumor necrosis factor receptor superfamily member 6; CD95; CD-95; Apo-1; Apo 1; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor]
• Other_names
  [tumor necrosis factor receptor superfamily member 6 isoform 1; Tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; Fas cell surface death receptor; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD_antigen: CD95]
• Products_gene_name
  [Fas]
• Other_gene_names
  [FAS; FAS; APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; APT1; FAS1; TNFRSF6]
• Clonality
  Monoclonal
• Clone
  [R-125224]
• Reactivity
  Human
• Specificity
  R-125224 binds to the extracellular portion of human Fas at an eptiope consisting of the sequence RTQNTKCRCK (aa 105-114) (pmid: 11754745). Fas is a type I membrane protein which belongs to the tumor necrosis factor (TNF) receptor/nerve growth factor (NGF) receptor superfamily. It is able to transduce apoptotic signals into the cell when bound by its ligand FasL (Fas ligand), which is primarily expressed in activated T lymphoid-myeloid lineage cells, in the eye, in reproductive organs and in some tumors. The Fas-FasL system is known to play an important role in maintaining the immune system as mice with Fas-defective lymphoproliferation (lpr) and FasL-defective generalized lymphoproliferative disease (gld) mutations develop massive lymphadenopathy and autoimmune diseases.
• Purity
  Protein A Affinity Purified
• Concentration
  1 mg/ml
• Storage_stability
  Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
• Tested_application
  Activate, Imaging, ELISA (EIA), Flow Cytometry (FC/FACS)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

• Gene target
  Fas   [R-125224]  
• Gene symbol
  RRAS, DAD1P1, HNRNPR, CLDN4, MC1R, PTPRK, CTNNA2, MTNR1A, H2AC19, CRHR1
• Short name
  Anti-Fas [R-125224]
• Technique
  anti-, anti, antibody to, antibodies
• Isotype
  Human IgG1, Kappa
• Alternative name
  Antibody toFas [R-125224]
• Alternative technique
  antibodies
• Alternative to gene target
  Fas (TNF receptor superfamily, member 6), ALPS1A and APO-1 and APT1 and CD95 and FAS1 and FASTM and TNFRSF6, FAS and IDBG-81669 and ENSG00000026103 and 355, identical protein binding, nuclei, Fas and IDBG-159577 and ENSMUSG00000024778 and 14102, FAS and IDBG-637356 and ENSBTAG00000010785 and 282488

Gene info

• Identity
  HGNC:10447
• Gene
  RRAS
• Long gene name
  RAS related
• Synonyms gene name
  • related RAS viral (r-ras) oncogene homolog
• Synonyms
  • R-Ras
• Synonyms name
  • Oncogene RRAS
• Locus
  19q13.33
• Discovery year
  2001-06-22
• Entrez gene record
  6237
• Pubmed identfication
  • 3098437
• RefSeq identity
  • NM_006270
• Classification
  • RAS type GTPase family
• VEGA ID
  OTTHUMG00000183247

Gene info

• Identity
  HGNC:18295
• Gene
  DAD1P1
• Long gene name
  defender against cell death 1 pseudogene 1
• Synonyms gene
  • DAD1L
• Synonyms gene name
  • defender against cell death 1-like
• Synonyms
  • DAD-R
• Locus
  12p12.1
• Discovery year
  2007-07-26
• Entrez gene record
  56286
• Pubmed identfication
  • 10812081
  • 11912161
• RefSeq identity
  • NR_024064

Gene info

• Identity
  HGNC:5047
• Gene
  HNRNPR
• Long gene name
  heterogeneous nuclear ribonucleoprotein R
• Synonyms gene
  • HNRPR
• Synonyms
  • hnRNP-R
• GenBank acession
  • AF000364
• Locus
  1p36.12
• Discovery year
  1999-06-11
• Entrez gene record
  10236
• Pubmed identfication
  • 9421497
• RefSeq identity
  • NM_005826
• Classification
  • Heterogeneous nuclear ribonucleoproteins
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000003224

Gene info

• Identity
  HGNC:2046
• Gene
  CLDN4
• Long gene name
  claudin 4
• Synonyms gene
  • CPETR
  • CPETR1
• Synonyms
  • CPE-R
  • WBSCR8
  • hCPE-R
• Synonyms name
  • Clostridium perfringens enterotoxin receptor 1
  • Williams-Beuren syndrome chromosomal region 8 protein
• GenBank acession
  • AB000712
• Locus
  7q11.23
• Discovery year
  1998-04-22
• Entrez gene record
  1364
• Pubmed identfication
  • 9334247
  • 9892664
• RefSeq identity
  • NM_001305
• Classification
  • Claudins
• VEGA ID
  OTTHUMG00000023425

Gene info

• Identity
  HGNC:6929
• Gene
  MC1R
• Long gene name
  melanocortin 1 receptor
• Synonyms gene name
  • melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
• Synonyms
  • MSH-R
• Synonyms name
  • alpha melanocyte stimulating hormone receptor
• Locus
  16q24.3
• Discovery year
  1993-07-27
• Entrez gene record
  4157
• Pubmed identfication
  • 8458079
• RefSeq identity
  • NM_002386
• Classification
  • Melanocortin receptors
• VEGA ID
  OTTHUMG00000171163

Gene info

• Identity
  HGNC:9674
• Gene
  PTPRK
• Long gene name
  protein tyrosine phosphatase receptor type K
• Synonyms
  • R-PTP-kappa
• GenBank acession
  • L77886
• Locus
  6q22.33
• Discovery year
  1998-02-09
• Entrez gene record
  5796
• Pubmed identfication
  • 9047348
  • 8663237
• Classification
  • Protein tyrosine phosphatases receptor type
  • Fibronectin type III domain containing
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000015536

Gene info

• Identity
  HGNC:2510
• Gene
  CTNNA2
• Long gene name
  catenin alpha 2
• Synonyms gene name
  • catenin (cadherin-associated protein), alpha 2
• Synonyms
  • CAP-R
  • CT114
• Synonyms name
  • cadherin-associated protein, related
  • cancer/testis antigen 114
  • alpha-N-catenin
• Locus
  2p12
• Discovery year
  1993-07-13
• Entrez gene record
  1496
• Pubmed identfication
  • 8432524
• RefSeq identity
  • NM_004389
• Classification
  • Alpha catenins
• VEGA ID
  OTTHUMG00000152903

Gene info

• Identity
  HGNC:7463
• Gene
  MTNR1A
• Long gene name
  melatonin receptor 1A
• Synonyms
  • MEL-1A-R
• Locus
  4q35.2
• Discovery year
  1995-03-22
• Entrez gene record
  4543
• Pubmed identfication
  • 7558006
• Classification
  • Melatonin receptors
• VEGA ID
  OTTHUMG00000185575

Gene info

• Identity
  HGNC:29668
• Gene
  H2AC19
• Long gene name
  H2A clustered histone 19
• Synonyms gene
  • HIST2H2AA4
• Synonyms gene name
  • histone 2, H2aa4
  • histone cluster 2, H2aa4
  • histone cluster 2 H2A family member a4
• Synonyms
  • H2A/r
• GenBank acession
  • L19779
• Locus
  1q21.2
• Discovery year
  2006-06-12
• Entrez gene record
  723790
• Pubmed identfication
  • 15527963
• RefSeq identity
  • NM_001040874
• Classification
  • H2A histones
• VEGA ID
  OTTHUMG00000012097

Gene info

• Identity
  HGNC:2357
• Gene
  CRHR1
• Long gene name
  corticotropin releasing hormone receptor 1
• Synonyms gene
  • CRHR
• Synonyms
  • CRF-R
  • CRF1
• Synonyms name
  • corticotropin-releasing factor receptor
• GenBank acession
  • L23332
• Locus
  17q21.31
• Discovery year
  1993-12-13
• Entrez gene record
  1394
• Pubmed identfication
  • 7590738
• Classification
  • Corticotropin releasing hormone receptors
• VEGA ID
  OTTHUMG00000178271

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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