Anti-CD80 [IDEC-114 (Galiximab)]

• Catalog number
  MBS488347
• Price
  Please ask
• Size
  0.2 mg

• Products_type
  Recombinant Antibody
• Products_short_name
  [CD80]
• Products_name_syn
  [B7-1; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7]
• Other_names
  [T-lymphocyte activation antigen CD80; T-lymphocyte activation antigen CD80; T-lymphocyte activation antigen CD80; CD80 molecule; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD_antigen: CD80]
• Products_gene_name
  [CD80]
• Other_gene_names
  [CD80; CD80; B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1; CD28LG; CD28LG1; LAB7; B7]
• Clonality
  Monoclonal
• Clone
  [IDEC-114]
• Reactivity
  Human
• Specificity
  Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to CD80. CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.
• Purity
  Protein A Affinity Purified
• Concentration
  1 mg/ml
• Storage_stability
  Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
• Tested_application
  Block (BL), Modulate, Flow Cytometry (FC/FACS), Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP), Immunohistochemistry (IHC)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

• Gene target
  CD80   [IDEC-114   Galiximab  
• Gene symbol
  CD80, REXO2, CDK5RAP3, OR4H6P
• Short name
  Anti-CD80 [IDEC-114 (Galiximab)]
• Technique
  anti-, anti, antibody to, antibodies
• Isotype
  Human IgG1, Lambda
• Alternative name
  Antibody toCD80 [IDEC-114 (Galiximab)]
• Alternative technique
  antibodies
• Alternative to gene target
  CD80 molecule, B7 and B7-1 and B7.1 and BB1 and CD28LG and CD28LG1 and LAB7, CD80 and IDBG-51287 and ENSG00000121594 and 941, coreceptor activity, Cell surfaces, Cd80 and IDBG-160288 and ENSMUSG00000075122 and 12519, BT.27986 and IDBG-632750 and ENSBTAG00000018059 and 407131

Gene info

• Identity
  HGNC:1700
• Gene
  CD80
• Long gene name
  CD80 molecule
• Synonyms gene
  • CD28LG
  • CD28LG1
• Synonyms gene name
  • CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)
  • CD80 molecule
• Synonyms
  • B7.1
  • B7-1
• Synonyms name
  • B-lymphocyte activation antigen B7
• Locus
  3q13.33
• Discovery year
  1993-12-14
• Entrez gene record
  941
• Pubmed identfication
  • 1370389
• RefSeq identity
  • NM_005191
• Classification
  • B7 family
  • CD molecules
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000159419

Gene info

• Identity
  HGNC:17851
• Gene
  REXO2
• Long gene name
  RNA exonuclease 2
• Synonyms gene name
  • REX2, RNA exonuclease 2 homolog (S. cerevisiae)
• Synonyms
  • DKFZP566E144
  • SFN
  • CGI-114
• GenBank acession
  • AF151872
• Locus
  11q23.2
• Discovery year
  2005-08-19
• Entrez gene record
  25996
• Pubmed identfication
  • 10851236
  • 10810093
  • 23741365
• RefSeq identity
  • NM_015523
• Classification
  • Exonucleases
• VEGA ID
  OTTHUMG00000168271

Gene info

• Identity
  HGNC:18673
• Gene
  CDK5RAP3
• Long gene name
  CDK5 regulatory subunit associated protein 3
• Synonyms
  • MST016
  • FLJ13660
  • C53
  • IC53
  • HSF-27
  • OK/SW-cl.114
  • LZAP
• Synonyms name
  • ischemic heart CDK5 activator-binding protein C53
  • LXXLL/leucine-zipper-containing ARFbinding protein
• GenBank acession
  • AF110322
• Locus
  17q21.32
• Discovery year
  2002-07-22
• Entrez gene record
  80279
• Pubmed identfication
  • 10721722
• RefSeq identity
  • NM_176096
• VEGA ID
  OTTHUMG00000178682

Gene info

• Identity
  HGNC:8312
• Gene
  OR4H6P
• Long gene name
  olfactory receptor family 4 subfamily H member 6 pseudogene
• Synonyms gene
  • OR4H9P
  • OR4H10P
  • OR4H5P
  • OR4H11P
  • OR4H5
  • OR4H7
  • OR4H7P
  • OR4H2P
  • OR4H3P
  • OR4H11
  • OR4H2
  • OR4H3
  • OR4H1P
  • OR4H4P
  • OR4H10
  • OR4H4
  • OR4H8P
  • OR4H8
• Synonyms gene name
  • olfactory receptor, family 4, subfamily H, member 8 pseudogene
  • olfactory receptor, family 4, subfamily H, member 6 pseudogene
• Synonyms
  • OR15-71
  • OR4H6
  • OR15-82
  • OR4H9
  • OR5-39
  • OR5-84
  • OR4-114
  • OR4-115
  • OR4-119
  • OR15-69
  • OR15-80
  • OR15-81
  • OR14-58
• GenBank acession
  • U86230
• Locus
  15q11.2
• Discovery year
  1999-11-25
• Entrez gene record
  26322
• Pubmed identfication
  • 9500546
• Classification
  • Olfactory receptors, family 4
• VEGA ID
  OTTHUMG00000172787

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