Anti-CD105 [MJ7/18]

• Catalog number
  MBS488440
• Price
  Please ask
• Size
  0.2 mg

• Products_type
  Recombinant Antibody
• Products_short_name
  [CD105]
• Products_name_syn
  [Endoglin; Cell surface MJ7/18 antigen]
• Other_names
  [endoglin isoform 1; Endoglin; endoglin; endoglin; Cell surface MJ7/18 antigen; CD_antigen: CD105]
• Products_gene_name
  [CD105]
• Other_gene_names
  [Eng; Eng; Endo; CD105; AI528660; AI662476; S-endoglin; Edg]
• Clonality
  Monoclonal
• Clone
  [MJ7/18]
• Reactivity
  Mouse
• Specificity
  MJ7/18 binds specifically to mouse CD105. CD105 is a homodimer expressed by vascular endothelial cells. CD105 functions in adhesion and embryonic angiogenesis. CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.
• Purity
  Protein A Affinity Purified
• Form
  PBS with 0.02% Proclin 300.
• Concentration
  1mg/ml
• Storage_stability
  Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
• Tested_application
  Flow Cytometry (FC/FACS), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

• Gene target
  CD105   [MJ7/18]  
• Gene symbol
  ENG
• Short name
  Anti-CD105 [MJ7/18]
• Technique
  anti-, anti, antibody to, antibodies
• Isotype
  Rabbit IgG kappa
• Alternative name
  Antibody toCD105 [MJ7/18]
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3349
• Gene
  ENG
• Long gene name
  endoglin
• Synonyms gene
  • ORW1
  • ORW
• Synonyms gene name
  • Osler-Rendu-Weber syndrome 1
• Synonyms
  • END
  • HHT1
  • CD105
• GenBank acession
  • AF035753
• Locus
  9q34.11
• Discovery year
  1993-03-03
• Entrez gene record
  2022
• Pubmed identfication
  • 8404038
  • 10548503
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000020723
• Locus Specific Databases
  • Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database
  • LRG_589

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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