Akt Substrate, 160kD, phosphorylated (Ser666) (AS160, DKFZp779C0666, KIAA0603, TBC1 domain family member 4, Rab GAP)

• Catalog number
  MBS619570
• Price
  Please ask
• Size
  5x0.25 mL

• Products_type
  Antibody
• Products_short_name
  [Akt Substrate, 160kD]
• Products_name_syn
  [Anti -Akt Substrate, 160kD, phosphorylated (Ser666) (AS160, DKFZp779C0666, KIAA0603, TBC1 domain family member 4, Rab GAP)]
• Other_names
  [Akt1, isoform B; RAC serine/threonine-protein kinase; CG4006 gene product from transcript CG4006-RA; Akt kinase; Akt1; Akt1-PA; Akt1-PB; Akt1-PC; CG4006-PA; CG4006-PB; CG4006-PC; dAkt kinase; protein kinase B; related to PKA to PKC protein kinases; related to the A and C kinases; Akt; Protein kinase B]
• Other_gene_names
  [Akt1; Akt1; akt; Akt; AKT; Akt/PKB; AKT/PKB; akt1; AKT1; Akt1|PKB; CG4006; D-Akt; dakt; dAkt; dAKT; Dakt; DAkt; dAKT/dPKB; dAkt/PKB; dakt1; dAkt1; dAKT1; Dakt1; DAkt1; DAKT1; DAKT1/PKB; DmelCG4006; dPKB; Dpkb; DPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq;; DAkt; DRAC-PK; Dakt1; PKB]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human AS160 when phosphorylated on Ser666. Species sequence homology: mouse (79%), cow, horse, and dog (90%).
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in 0.1M Tris-Glycine, pH7.4, 150mM sodium chloride, 0.05% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  Western Blot (WB)

• Gene target
  Akt   Substrate   160kD   phosphorylated   Ser666   AS160   DKFZp779C0666   KIAA0603   TBC1   domain   family   member   Rab   GAP  
• Gene symbol
  TBC1D4, TBC1D1, GAP43, ARHGAP32, ITGA3, RASA1
• Short name
  Akt Substrate, 160kD, phosphorylated (Ser666) (AS160, DKFZp779C0666, KIAA0603, TBC1 domain family member 4, Rab GAP)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  Akt Substrate, 160kD, phosphorylated (Ser666) (AS160, DKFZp779C0666, KIAA0603, TBC1 domain family member 4, Rab GAP)

Gene info

• Identity
  HGNC:19165
• Gene
  TBC1D4
• Long gene name
  TBC1 domain family member 4
• Synonyms gene name
  • TBC1 domain family, member 4
• Synonyms
  • KIAA0603
  • AS160
  • DKFZp779C0666
• Synonyms name
  • Akt substrate of 160 kDa
• GenBank acession
  • AB011175
• Locus
  13q22.2
• Discovery year
  2002-08-29
• Entrez gene record
  9882
• Pubmed identfication
  • 11829485
  • 11994271
  • 15304337
• RefSeq identity
  • NM_014832
• VEGA ID
  OTTHUMG00000017088

Gene info

• Identity
  HGNC:11578
• Gene
  TBC1D1
• Long gene name
  TBC1 domain family member 1
• Synonyms gene name
  • TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
  • TBC1 domain family, member 1
• Synonyms
  • TBC
  • TBC1
  • KIAA1108
• GenBank acession
  • AB029031
• Locus
  4p14
• Discovery year
  2000-03-06
• Entrez gene record
  23216
• Pubmed identfication
  • 10965142
  • 18258599
• RefSeq identity
  • NM_015173
• VEGA ID
  OTTHUMG00000150302

Gene info

• Identity
  HGNC:4140
• Gene
  GAP43
• Long gene name
  growth associated protein 43
• Synonyms
  • B-50
  • PP46
  • GAP-43
• Synonyms name
  • neuron growth-associated protein 43
  • neuromodulin
  • nerve growth-related peptide GAP43
  • axonal membrane protein GAP-43
  • protein F1
  • calmodulin-binding protein P-57
  • neural phosphoprotein B-50
• Locus
  3q13.31
• Discovery year
  1990-07-10
• Entrez gene record
  2596
• Pubmed identfication
  • 3272162
  • 8231732
• RefSeq identity
  • NM_002045
• VEGA ID
  OTTHUMG00000133758

Gene info

• Identity
  HGNC:17399
• Gene
  ARHGAP32
• Long gene name
  Rho GTPase activating protein 32
• Synonyms
  • GRIT
  • KIAA0712
  • MGC1892
  • RICS
  • GC-GAP
• GenBank acession
  • AB018255
• Locus
  11q24.3
• Discovery year
  2010-02-19
• Entrez gene record
  9743
• Pubmed identfication
  • 12446789
  • 12819203
  • 17663722
• RefSeq identity
  • NM_014715
• Classification
  • Rho GTPase activating proteins
• VEGA ID
  OTTHUMG00000165774

Gene info

• Identity
  HGNC:6139
• Gene
  ITGA3
• Long gene name
  integrin subunit alpha 3
• Synonyms gene
  • MSK18
• Synonyms gene name
  • antigen identified by monoclonal antibody J143
  • integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
• Synonyms
  • CD49c
  • VLA3a
  • VCA-2
  • GAP-B3
• Synonyms name
  • alpha 3 subunit of VLA-3 receptor
  • antigen CD49C
• GenBank acession
  • M59911
• Locus
  17q21.33
• Discovery year
  1992-02-27
• Entrez gene record
  3675
• Pubmed identfication
  • 1655803
  • 9704023
• RefSeq identity
  • NM_005501
• Classification
  • Integrin alpha subunits
  • CD molecules
• VEGA ID
  OTTHUMG00000161890

Gene info

• Identity
  HGNC:9871
• Gene
  RASA1
• Long gene name
  RAS p21 protein activator 1
• Synonyms gene
  • RASA
• Synonyms gene name
  • RAS p21 protein activator (GTPase activating protein) 1
• Synonyms
  • GAP
  • CM-AVM
  • p120GAP
  • p120RASGAP
  • p120
• Synonyms name
  • capillary malformation-arteriovenous malformation
  • p120 RAS GTPase activating protein
• Locus
  5q14.3
• Discovery year
  1989-06-30
• Entrez gene record
  5921
• Pubmed identfication
  • 15917201
• RefSeq identity
  • NM_002890
• Classification
  • SH2 domain containing
  • C2 and RasGAP domain containing
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000162605
• Locus Specific Databases
  • SH2base: Database for pathogenic SH2 domain mutations

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