Adrenergic Receptor Kinase, beta 1 (bARK1, B1 AR, ARK1 beta, G Protein Coupled Receptor Kinase 2, GPCR K2, GRK2)

  • Catalog number
    MBS606474
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [Adrenergic Receptor Kinase, beta 1]
  • Products_name_syn
    [Anti -Adrenergic Receptor Kinase, beta 1 (bARK1, B1 AR, ARK1 beta, G Protein Coupled Receptor Kinase 2, GPCR K2, GRK2)]
  • Other_names
    [Adrenergic, beta, receptor kinase 1; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1; beta-ARK-1; OTTHUMP00000235171; G-protein coupled receptor kinase 2; adrenergic, beta, receptor kinase 1; G-protein coupled receptor kinase 2]
  • Other_gene_names
    [ADRBK1; ADRBK1; GRK2; BARK1; FLJ16718; BETA-ARK1; BARK; BARK1; GRK2]
  • Clonality
    Monoclonal
  • Clone
    [8H208]
  • Reactivity
    Human, Mouse, Rat
  • Specificity
    Recognizes human/mouse/rat GRK2.
  • Purity
    Purified Purified by Protein G affinity chromatography.
  • Form
    Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with sterile 40-50% glycerol, PBS.
  • Storage_stability
    Lyophilized powder may be stored at -20 degree C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested_application
    Western Blot (WB)
  • Description
    The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
    Adrenergic   Receptor   Kinase   beta   bARK1   ARK1   beta   Protein   Coupled   Receptor   Kinase   GPCR   GRK2  
  • Gene symbol
    GRK2, OXER1, HCAR1, AURKA, GPBAR1, GPER1
  • Short name
    Adrenergic Receptor Kinase, beta 1 (bARK1, B1 AR, ARK1 beta, G Protein Coupled Receptor Kinase 2, GPCR K2, GRK2)
  • Host
    Mouse
  • Isotype
    IgG2b
  • Alternative name
    Adrenergic Receptor phosphorylation catalyst, b 1 (bARK1, B1 AR, ARK1 b, G Protein Coupled Receptor phosphorylation catalyst 2, GPCR K2, GRK2)
Gene info
  • Identity
    HGNC:289
  • Gene
    GRK2
  • Long gene name
    G protein-coupled receptor kinase 2
  • Synonyms gene
  • Synonyms gene name
    • adrenergic, beta, receptor kinase 1
  • Synonyms
  • GenBank acession
  • Locus
    11q13.2
  • Discovery year
    1992-03-25
  • Entrez gene record
    156
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Pleckstrin homology domain containing
    • AGC family kinases
  • VEGA ID
    OTTHUMG00000167104
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
    Polymerase Chain Reaction
  • Concept
    Scope note: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
  • Tree numbers
    • E05.393.620.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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Filters
Adrenergic Receptor Kinase beta 1 bARK1 B1 AR ARK1 beta G Pr
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