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Products_type
Antibody
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Products_short_name
[Adenosine A1 Receptor]
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Products_name_syn
[Anti -Adenosine A1 Receptor]
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Other_names
[adenosine A1 receptor; Adenosine receptor A1; adenosine receptor A1; OTTHUMP00000039090; OTTHUMP00000039091; adenosine A1 receptor]
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Other_gene_names
[ADORA1; ADORA1; RDC7]
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Clonality
Polyclonal
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Reactivity
Guinea Pig, Human, Porcine, Rat, Sheep
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Specificity
Recognizes rat Adenosine A1 receptor (A1R) at 79 and 39kD bands in cortical membranes. The 79kD band can be converted to 39kD band by agonist or antagonist treatment and could represent A1R dimers. Species Crossreactivity: human, porcine, sheep and guinea pig.
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Purity
Affinity Purified Purified by affinity chromatography.
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Form
Supplied as a liquid in PBS, 0.1% BSA.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
