Activin Receptor Type IIB (RIIB)

• Catalog number
  MBS605715
• Price
  Please ask
• Size
  0.5 mg

• Products_type
  Antibody
• Products_short_name
  [Activin Receptor Type IIB]
• Products_name_syn
  [Anti -Activin Receptor Type IIB (RIIB)]
• Other_names
  [activin receptor type IIB; Activin receptor type-2B; activin receptor type-2B; OTTHUMP00000161965; activin A receptor, type IIB; Activin receptor type IIB]
• Other_gene_names
  [ACVR2B; ACVR2B; HTX4; ACTRIIB; ActR-IIB; MGC116908]
• Clonality
  Monoclonal
• Clone
  [9H21]
• Reactivity
  Human
• Specificity
  Recognizes recombinant human Activin RIIB. Shows ~5% crossreactivity with recombinant human Activin RIIA.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
• Storage_stability
  Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Activin   Receptor   IIB   RIIB  
• Gene symbol
  ACVR2B, MYH4
• Short name
  Activin Receptor IIB (RIIB)
• Host
  Mouse
• Isotype
  IgG1
• Alternative name
  Activin Receptor classification IIB (RIIB)

Gene info

• Identity
  HGNC:174
• Gene
  ACVR2B
• Long gene name
  activin A receptor type 2B
• Synonyms gene name
  • activin A receptor, type IIB
• Synonyms
  • ActR-IIB
• GenBank acession
  • X77533
• Locus
  3p22.2
• Discovery year
  1997-03-19
• Entrez gene record
  93
• Pubmed identfication
  • 8161782
  • 9621519
• RefSeq identity
  • NM_001106
• Classification
  • Type 2 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000131291

Gene info

• Identity
  HGNC:7574
• Gene
  MYH4
• Long gene name
  myosin heavy chain 4
• Synonyms gene name
  • myosin, heavy polypeptide 4, skeletal muscle
• Synonyms
  • MYH2B
  • MyHC-2B
  • MyHC-IIb
• Locus
  17p13.1
• Discovery year
  1986-01-01
• Entrez gene record
  4622
• Pubmed identfication
  • 8518795
• RefSeq identity
  • NM_017533
• Classification
  • Myosin heavy chains, class II
• VEGA ID
  OTTHUMG00000130365

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