Activating Transcription Factor 2, phosphorylated (Thr53, Thr71) (ATF2, CREB P1)

• Catalog number
  MBS630109
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [Activating Transcription Factor 2]
• Products_name_syn
  [Anti -Activating Transcription Factor 2, phosphorylated (Thr53, Thr71) (ATF2, CREB P1)]
• Other_names
  [activating transcription factor 2; activating transcription factor 2; cyclic AMP response element binding protein 2]
• Other_gene_names
  [ATF2; CREB2; MGC142504]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Detects endogenous levels of ATF-2 only when phosphorylated at threonine 71 or 53.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.
• Storage_stability
  For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  Western Blot (WB), Immunohistochemistry (IHC)
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  Activating   Transcription   Factor   phosphorylated   Thr53   Thr71   ATF2   CREB  
• Gene symbol
  CREB3L3, GDNF, ATF4, ATF2
• Short name
  Activating Transcription Factor 2, phosphorylated (Thr53, Thr71) (ATF2, CREB P1)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  Activating Transcription Factor 2, phosphorylated (Thr53, Thr71) (ATF2, CREB P1)

Gene info

• Identity
  HGNC:18855
• Gene
  CREB3L3
• Long gene name
  cAMP responsive element binding protein 3 like 3
• Synonyms
  • CREB-H
  • CREBH
• Synonyms name
  • cAMP-responsive element-binding protein, hepatic-specific
• Locus
  19p13.3
• Discovery year
  2003-12-09
• Entrez gene record
  84699
• Pubmed identfication
  • 11353085
• RefSeq identity
  • NM_032607
• Classification
  • CREB3 transcription factor family
• VEGA ID
  OTTHUMG00000181846

Gene info

• Identity
  HGNC:4232
• Gene
  GDNF
• Long gene name
  glial cell derived neurotrophic factor
• Synonyms
  • ATF1
  • ATF2
  • HFB1-GDNF
• Synonyms name
  • astrocyte-derived trophic factor
  • glial cell line derived neurotrophic factor
  • glial derived neurotrophic factor
• Locus
  5p13.2
• Discovery year
  1995-05-04
• Entrez gene record
  2668
• Pubmed identfication
  • 8493557
• RefSeq identity
  • NM_000514
• Classification
  • GDNF family ligands
• VEGA ID
  OTTHUMG00000090809

Gene info

• Identity
  HGNC:786
• Gene
  ATF4
• Long gene name
  activating transcription factor 4
• Synonyms gene
  • TXREB
• Synonyms gene name
  • activating transcription factor 4 (tax-responsive enhancer element B67)
• Synonyms
  • TAXREB67
  • CREB-2
• Synonyms name
  • tax-responsive enhancer element B67
• GenBank acession
  • D90209
• Locus
  22q13.1
• Discovery year
  1992-06-09
• Entrez gene record
  468
• Pubmed identfication
  • 1847461
  • 1534408
• RefSeq identity
  • NM_001675
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000151099

Gene info

• Identity
  HGNC:784
• Gene
  ATF2
• Long gene name
  activating transcription factor 2
• Synonyms gene
  • CREB2
• Synonyms gene name
  • cAMP responsive element binding protein 2
• Synonyms
  • TREB7
  • CRE-BP1
  • HB16
• GenBank acession
  • X15875
• Locus
  2q31.1
• Discovery year
  1991-08-01
• Entrez gene record
  1386
• Pubmed identfication
  • 1833307
  • 1838349
• RefSeq identity
  • NM_001880
• Classification
  • Basic leucine zipper proteins
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000132424

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