Kallikrein Inhibitor

Alternative_Names

AC-Pro-Phe-Arg-Ser-Val-Gln-NH2;Ac-PFRSVQ-NH2
CAS

97145-43-2
MWt

773.88
Formula

C35H55N11O9
Solubility

DMSO
Clinical_Information

Phase 2
Pathway

Others
Target

Others
Datasheet
SDS
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Identity

HGNC:6169
Gene

ITIH4
Long gene name

inter-alpha-trypsin inhibitor heavy chain 4
Synonyms gene
- ITIHL1
Synonyms gene name
- inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)
- inter-alpha-trypsin inhibitor heavy chain family, member 4
Synonyms
- IHRP
- H4P
Synonyms name
- plasma Kallikrein-sensitive glycoprotein
GenBank acession
- D38535
Locus

3p21.1
Discovery year

1995-11-30
Entrez gene record

3700
Pubmed identfication
- 9480842
- 7805892
RefSeq identity
- NM_002218
Classification
- Inter-alpha-trypsin inhibitor heavy chains
VEGA ID

OTTHUMG00000159023