E3 ligase Ligand 1

• Catalog number
  HY-42424
• Price
  Please ask
• Size
  1g

• Alternative_Names
  NA
• CAS
  1948273-03-7
• MWt
  481.05
• Formula
  C23H33ClN4O3S
• Solubility
  DMSO
• Clinical_Information
  No Development Reported
• Pathway
  PROTAC
• Target
  Ligand for E3 Ligase
• Datasheet
• SDS
• Description
  FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

• Gene target
  ligase   Ligand  
• Gene symbol
  LNX1
• Short name
  E3 ligase Ligand 1
• Alternative name
  E3 ligase Ligand 1

Gene info

• Identity
  HGNC:6657
• Gene
  LNX1
• Long gene name
  ligand of numb-protein X 1
• Synonyms gene
  • LNX
• Synonyms gene name
  • ligand of numb-protein X
  • ligand of numb-protein X 1, E3 ubiquitin protein ligase
• Synonyms
  • MPDZ
  • PDZRN2
• GenBank acession
  • AF237782
• Locus
  4q12
• Discovery year
  2000-05-31
• Entrez gene record
  84708
• Pubmed identfication
  • 11521506
  • 11782429
• Classification
  • Ring finger proteins
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000102099

MeSH Data

• Name
  Ligase Chain Reaction
• Concept
  Scope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
• Tree numbers
  • E05.393.620.311
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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