BET bromodomain inhibitor

• Catalog number
  HY-103036
• Price
  Please ask
• Size
  5mg

• Alternative_Names
  NA
• CAS
  1505453-59-7
• MWt
  445.90
• Formula
  C24H20ClN5O2
• Solubility
  DMSO: ≥100 mg/mL
• Clinical_Information
  No Development Reported
• Pathway
  Epigenetics
• Target
  Epigenetic Reader Domain
• Datasheet
• SDS
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  BET   bromodomain   inhibitor  
• Gene symbol
  DNER, TBX21
• Short name
  BET bromodomain inhibitor
• Alternative name
  BET bromodomain suppressor

Gene info

• Identity
  HGNC:24456
• Gene
  DNER
• Long gene name
  delta/notch like EGF repeat containing
• Synonyms gene name
  • delta/notch-like EGF repeat containing
• Synonyms
  • UNQ26
  • bet
• GenBank acession
  • AY358891
• Locus
  2q36.3
• Discovery year
  2006-10-26
• Entrez gene record
  92737
• Pubmed identfication
  • 11950833
  • 11997712
• RefSeq identity
  • NM_139072
• VEGA ID
  OTTHUMG00000153637

Gene info

• Identity
  HGNC:11599
• Gene
  TBX21
• Long gene name
  T-box transcription factor 21
• Synonyms gene name
  • T-box 21
• Synonyms
  • TBLYM
  • T-bet
• GenBank acession
  • AF093098
• Locus
  17q21.32
• Discovery year
  2000-02-29
• Entrez gene record
  30009
• RefSeq identity
  • NM_013351
• Classification
  • T-box transcription factors
• VEGA ID
  OTTHUMG00000178287

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