ACT-132577

• Catalog number
  HY-15895
• Price
  Please ask
• Size
  100mg

• Alternative_Names
  aprocitentan
• CAS
  1103522-45-7
• MWt
  546.19
• Formula
  C16H14Br2N6O4S
• Solubility
  DMSO: ≥ 46 mg/mL
• Clinical_Information
  Phase 1
• Pathway
  GPCR/G Protein
• Target
  Endothelin Receptor
• Datasheet
• SDS

• Gene target
  ACT-132577  
• Gene symbol
  SERPINA3, POTEM, FHL5, CISTR, ACOT7, CCL4, TRS-ACT1-1
• Short name
  ACT-132577
• Alternative name
  ACT-132577

Gene info

• Identity
  HGNC:16
• Gene
  SERPINA3
• Long gene name
  serpin family A member 3
• Synonyms gene
  • AACT
• Synonyms gene name
  • alpha-1-antichymotrypsin
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
• Synonyms
  • ACT
• Synonyms name
  • alpha-1 antichymotrypsin
• GenBank acession
  • K01500
• Locus
  14q32.13
• Discovery year
  2001-06-22
• Entrez gene record
  12
• Pubmed identfication
  • 3260956
  • 24172014
• RefSeq identity
  • NM_001085
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000029851

Gene info

• Identity
  HGNC:37096
• Gene
  POTEM
• Long gene name
  POTE ankyrin domain family member M
• Synonyms gene name
  • POTE ankyrin domain family, member M
• Synonyms
  • POTE14beta
  • P704P
  • ACT
• Synonyms name
  • prostate-specific P704P
• Locus
  14q11.2
• Discovery year
  2009-06-04
• Entrez gene record
  641455
• Pubmed identfication
  • 16364570
• RefSeq identity
  • NM_001145442
• Classification
  • POTE ankyrin domain containing
• VEGA ID
  OTTHUMG00000170340

Gene info

• Identity
  HGNC:17371
• Gene
  FHL5
• Long gene name
  four and a half LIM domains 5
• Synonyms
  • FLJ33049
  • ACT
  • dJ393D12.2
• GenBank acession
  • AF278541
• Locus
  6q16.1
• Discovery year
  2003-11-26
• Entrez gene record
  9457
• RefSeq identity
  • NM_020482
• Classification
  • LIM domain containing
• VEGA ID
  OTTHUMG00000015239

Gene info

• Identity
  HGNC:49426
• Gene
  CISTR
• Long gene name
  chondrogenesis-associated transcript
• Synonyms
  • CISTR-ACT
  • CISTRACT
  • re52431
• Synonyms name
  • cis- and trans-chromosomal chondrogenic regulator transcript
• GenBank acession
  • DA125942
  • HY042141
• Locus
  12q13.13
• Discovery year
  2014-01-14
• Entrez gene record
  102216268
• Pubmed identfication
  • 23093776
• RefSeq identity
  • NR_104332
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000173078

Gene info

• Identity
  HGNC:24157
• Gene
  ACOT7
• Long gene name
  acyl-CoA thioesterase 7
• Synonyms
  • BACH
  • ACH1
  • ACT
  • CTE-II
  • LACH1
  • MGC1126
  • hBACH
• Synonyms name
  • brain acyl CoA hydrolase
  • Long chain acyl-CoA thioester hydrolase
• GenBank acession
  • AB074417
• Locus
  1p36.31
• Discovery year
  2005-09-07
• Entrez gene record
  11332
• Pubmed identfication
  • 10578051
  • 16103133
  • 16940157
• RefSeq identity
  • NM_007274
• Classification
  • Acyl-CoA thioesterases
• VEGA ID
  OTTHUMG00000001295

Gene info

• Identity
  HGNC:10630
• Gene
  CCL4
• Long gene name
  C-C motif chemokine ligand 4
• Synonyms gene
  • LAG1
  • SCYA4
• Synonyms gene name
  • small inducible cytokine A4 (homologous to mouse Mip-1b)
  • chemokine (C-C motif) ligand 4
• Synonyms
  • MIP-1-beta
  • Act-2
  • AT744.1
• GenBank acession
  • M23502
• Locus
  17q12
• Discovery year
  1990-07-05
• Entrez gene record
  6351
• Pubmed identfication
  • 1972563
• RefSeq identity
  • NM_002984
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188414

Gene info

• Identity
  HGNC:35102
• Gene
  TRS-ACT1-1
• Long gene name
  tRNA-Ser (anticodon ACT) 1-1
• Synonyms gene
  • TRNAS32P
• Synonyms gene name
  • transfer RNA serine 32 (anticodon ACU) pseudogene
  • transfer RNA-Ser (ACT) 1-1
• Synonyms
  • tRNA-Ser-ACT-1-1
• GenBank acession
  • HG984007
• Locus
  6p22.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189526
• RefSeq identity
  • NG_008584
• Classification
  • Cytoplasmic transfer RNA pseudogenes

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