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Long name
Recombinant Rat cAMP-dependent protein kinase inhibitor alpha (Pkia)
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Alternative names
cAMP-dependent protein kinase inhibitor alpha; cAMP-dependent protein kinase inhibitor alpha; cAMP-dependent protein kinase inhibitor alpha; PKI-alpha; protein kinase inhibitor, alpha; cAMP-dependent protein kinase inhibitor, muscle/brain isoform; protein kinase (cAMP-dependent, catalytic) inhibitor alpha; cAMP-dependent protein kinase inhibitor, muscle/brain isoform
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Gene name
Pkia
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Other gene names
Pkia; Pkia; PKI-alpha
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General description
cAMP-dependent protein kinase inhibitor alpha(Pkia) is a recombinant protein expressed in E. coli. The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.
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Product category
Recombinant Proteins
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Expression system
E. coli
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Available also expressed in
E Coli ; Yeast ; Baculovirus ; Mammalian Cell
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Purity
Greater than 90% (determined by SDS-PAGE)
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Form
Lyophilized protein
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Storage
This protein can be stored at -20 degrees Celsius. For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius. Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains.
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Applications
This protein can be used as a positive control for applications such as ELISA, IFA, RIA, Western Blot, etc.
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Description
The cAMP-dependent protein kinase inhibitor alpha(Pkia) is a α- or alpha protein sometimes glycoprotein present in blood. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
