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Long name
Recombinant Mouse Neuronal acetylcholine receptor subunit alpha-4 (Chrna4)
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Alternative names
neuronal acetylcholine receptor subunit alpha-4; Neuronal acetylcholine receptor subunit alpha-4; neuronal acetylcholine receptor subunit alpha-4; alpha4 nAChR; alpha4-nAChR; a4 nicotinic receptor; acetylcholine receptor alpha 4 neural; acetylcholine receptor, neuronal, nicotinic, alpha-4 subunit; cholinergic receptor, nicotinic, alpha polypeptide 4;
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Gene name
N/A
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Other gene names
Chrna4; Chrna4; EBN1; Acra4; ENFL1; Acra-4; Acra4
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General description
Neuronal acetylcholine receptor subunit alpha-4 (Chrna4) is a recombinant protein expressed in E. coli. The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.
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Product category
Recombinant Proteins
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Expression system
E. coli
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Available also expressed in
E Coli ; Yeast
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Purity
Greater than 90% (determined by SDS-PAGE)
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Form
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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Storage
This protein can be stored at -20 degrees Celsius. For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius. Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains.
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Applications
This protein can be used as a positive control for applications such as ELISA, IFA, RIA, Western Blot, etc.
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Description
The Neuronal acetylcholine receptor subunit alpha-4 (Chrna4) is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Gene symbol
CHRNA4
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Short name
Neuronal acetylcholine receptor subunit alpha-4 (Chrna4)
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Technique
Mouse, mouses
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Host
mouse, Escherichia coli, Recombination of bioactive proteins and longer peptides in Escherichia Coli is done often with His tagging. MBS Recombinant supplies Rec. E. Coli affinity purified or tag purified antigens in 1 quantities or bulk volumes on request.
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Species
E. coli, E. coli, Mouses
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Alternative name
Mouse Neuronal acetylcholine receptor functionnal sequence a-4 (cholinergic receptor, nicotinic, a 4 (neuronal))-E. coli
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Alternative technique
murine, escherichia
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Alternative to gene target
cholinergic receptor, nicotinic, alpha 4 (neuronal), BFNC and EBN and EBN1 and NACHR and NACHRA4 and NACRA4, CHRNA4 and IDBG-86002 and ENSG00000101204 and 102723788,1137, acetylcholine binding, Cell surfaces, Chrna4 and IDBG-213951 and ENSMUSG00000027577 and 11438, BT.35525 and IDBG-640656 and ENSBTAG00000017198 and 537251
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