Macaca nemestrina Tumor necrosis factor ligand superfamily member 6 (FASLG) -E. coli

• Catalog number
  GEN1083270.E.coli
• Price
  Please ask
• Size
  1000ug

• Long name
  Recombinant Macaca nemestrina Tumor necrosis factor ligand superfamily member 6 (FASLG)
• Alternative names
  Tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD_antigen: CD178Cleaved into the following 4 chains:Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble formAlternative name(s):Receptor-binding FasL ectodomain; Soluble Fas ligand; sFasL
• Gene name
  FASLG
• Other gene names
  FASLG; CD95L; FASL; TNFSF6; CD95-L; Fas ligand; FasL; sFasL; APL; FasL ICD; SPA
• General description
  Tumor necrosis factor ligand superfamily member 6(FASLG) is a recombinant protein expressed in E. coli. The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.
• Product category
  Recombinant Proteins
• Expression system
  E. coli
• Available also expressed in
  E Coli ; Yeast ; Baculovirus ; Mammalian Cell
• Purity
  Greater than 90% (determined by SDS-PAGE)
• Form
  Lyophilized protein
• Storage
  This protein can be stored at -20 degrees Celsius. For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius. Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains.
• Applications
  This protein can be used as a positive control for applications such as ELISA, IFA, RIA, Western Blot, etc.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

• Gene target
  Macaca   nemestrina   Tumor   necrosis   factor   ligand   superfamily   member   FASLG  
• Gene symbol
  FASLG
• Short name
  Tumor necrosis factor ligand superfamily member 6(FASLG)
• Host
  e. coli, Escherichia coli, Recombination of bioactive proteins and longer peptides in Escherichia Coli is done often with His tagging. MBS Recombinant supplies Rec. E. Coli affinity purified or tag purified antigens in 1 quantities or bulk volumes on request.
• Species
  E. coli, E. coli
• Alternative name
  Macaca nemestrina Tumor necrosis factor ligand supergroup member 6 (Fas (tumor necrosis factor receptor superfamily, member 6) ligand (tumor necrosis factor superfamily, member 6)) -E. coli
• Alternative technique
  escherichia
• Alternative to gene target
  Fas ligand (TNF superfamily, member 6), ALPS1B and APT1LG1 and APTL and CD178 and CD95-L and CD95L and FASL and TNFSF6, FASLG and IDBG-104856 and ENSG00000117560 and 356, protein binding, nuclei, Fasl and IDBG-201576 and ENSMUSG00000000817 and 14103, LOC407111 and IDBG-632305 and ENSBTAG00000032808 and 101908770,407111
• Tissue
  tumor

Gene info

• Identity
  HGNC:11936
• Gene
  FASLG
• Long gene name
  Fas ligand
• Synonyms gene
  • APT1LG1
  • TNFSF6
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 6
  • Fas ligand (TNF superfamily, member 6)
• Synonyms
  • FasL
  • CD178
• GenBank acession
  • U11821
• Locus
  1q24.3
• Discovery year
  1994-12-09
• Entrez gene record
  356
• Pubmed identfication
  • 7826947
  • 9022072
• Classification
  • Tumor necrosis factor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000034841
• Locus Specific Databases
  • FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base)
  • LRG_58

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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