Human Tumor necrosis factor receptor superfamily member EDAR (EDAR) -Mammalian Cell

• Catalog number
  GEN1287135.Mammalian Cell
• Price:

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• Size
  100ug

• Long name
  Recombinant Human Tumor necrosis factor receptor superfamily member EDAR (EDAR)
• Alternative names
  tumor necrosis factor receptor superfamily member EDAR; Tumor necrosis factor receptor superfamily member EDAR; tumor necrosis factor receptor superfamily member EDAR; EDA-A1 receptor; downless homolog; ectodysplasin-A receptor; downless, mouse, homolog of; ectodermal dysplasia receptor; anhidrotic ectodysplasin receptor 1; ectodysplasin 1, anhidrotic receptor; ectodysplasin A receptor; Anhidrotic ectodysplasin receptor 1; Downless homolog; EDA-A1 receptor; Ectodermal dysplasia receptor; Ectodysplasin-A receptor
• Gene name
  EDAR
• Other gene names
  EDAR; EDAR; DL; ED3; ED5; ED1R; EDA3; HRM1; EDA1R; ECTD10A; ECTD10B; EDA-A1R; DL
• General description
  Tumor necrosis factor receptor superfamily member EDAR (EDAR) is a recombinant protein expressed in Mammalian Cell . The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.
• Product category
  Recombinant Proteins
• Expression system
  Mammalian Cell
• Available also expressed in
  E Coli ; Yeast ; Baculovirus ; Mammalian Cell
• Purity
  Greater than 90% (determined by SDS-PAGE)
• Form
  Lyophilized protein
• Storage
  This protein can be stored at -20 degrees Celsius. For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius. Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains.
• Applications
  This protein can be used as a positive control for applications such as ELISA, IFA, RIA, Western Blot, etc.
• Description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Tumor   necrosis   factor   receptor   superfamily   member   EDAR   EDAR   Mammalian  
• Gene symbol
  EDAR
• Short name
  Tumor necrosis factor receptor superfamily member EDAR (EDAR)
• Species
  Human, Humans
• Alternative name
  H. sapiens Tumor necrosis factor receptor supergroup member ectodysplasin A receptor (ectodysplasin A receptor) -Mammalian cellular
• Alternative to gene target
  ectodysplasin A receptor, DL and ECTD10A and ECTD10B and ED1R and ED3 and ED5 and EDA-A1R and EDA1R and EDA3 and HRM1, EDAR and IDBG-65178 and ENSG00000135960 and 10913, protein binding, Plasma membranes, Edar and IDBG-153317 and ENSMUSG00000003227 and 13608, EDAR and IDBG-634358 and ENSBTAG00000019628 and 613947
• Tissue
  cell, tumor

Gene info

• Identity
  HGNC:2895
• Gene
  EDAR
• Long gene name
  ectodysplasin A receptor
• Synonyms gene
  • ED3
  • DL
• Synonyms gene name
  • ectodysplasin 1, anhidrotic receptor
• Synonyms
  • ED5
  • EDA3
  • ED1R
  • EDA1R
• GenBank acession
  • AF130988
• Locus
  2q13
• Discovery year
  1999-08-09
• Entrez gene record
  10913
• Pubmed identfication
  • 10431241
  • 9375732
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000130982

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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