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Long name
Recombinant Human Suppressor of cytokine signaling 6 (SOCS6)
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Alternative names
suppressor of cytokine signaling 6; Suppressor of cytokine signaling 6; suppressor of cytokine signaling 6; STAT induced STAT inhibitor-4; cytokine-inducible SH2 protein 4; suppressor of cytokine signaling 4; suppressor of cytokine signaling 6; Cytokine-inducible SH2 protein 4; CIS-4; Suppressor of cytokine signaling 4; SOCS-4
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Gene name
SOCS6
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Other gene names
SOCS6; SOCS6; CIS4; SSI4; CIS-4; SOCS4; STAI4; SOCS-4; SOCS-6; STATI4; HSPC060; CIS4; SOCS4; SOCS-6; CIS-4; SOCS-4
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General description
Suppressor of cytokine signaling 6 (SOCS6) is a recombinant protein expressed in Yeast . The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.
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Product category
Recombinant Proteins
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Expression system
Yeast
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Available also expressed in
E Coli ; Yeast ; Baculovirus ; Mammalian Cell
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Purity
Greater than 90% (determined by SDS-PAGE)
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Form
Lyophilized protein
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Storage
This protein can be stored at -20 degrees Celsius. For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius. Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains.
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Applications
This protein can be used as a positive control for applications such as ELISA, IFA, RIA, Western Blot, etc.
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Description
Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
