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Long name
Recombinant human Advanced glycosylation end product-specific receptor
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Alternative names
advanced glycosylation end product-specific receptor; Advanced glycosylation end product-specific receptor; advanced glycosylation end product-specific receptor; receptor for advanced glycosylation end products; advanced glycosylation end product-specific receptor variant 2; advanced glycosylation end product-specific receptor variant 3; advanced glycosylation end product-specific receptor variant 4; advanced glycosylation end product-specific receptor variant 5; advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products
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Gene name
N/A
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Other gene names
Ager; Ager; RAGE; Rage
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General description
Advanced glycosylation end product-specific receptor is a recombinant protein expressed in . The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.
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Product category
Recombinant Proteins
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Available also expressed in
E Coli
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Purity
N/A
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Form
Lyophilized protein
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Storage
Store at -20 degree C. For extended storage, conserve at -20 or -80 degree C.
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Applications
This protein can be used as a positive control for applications such as ELISA, IFA, RIA, Western Blot, etc.
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Test
Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosylic donor, is attached to a hydroxyl or other functional group of another molecule (a glycosylic acceptor). In biology glycosylation mainly refers in particular to the enzymatic process that attaches glycans to proteins, lipids, or other organic molecules
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
