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Long name
Recombinant Cowpox virus Serine proteinase inhibitor 2 (CRMA)
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Alternative names
CrmA or CPXV207 protein; Serine proteinase inhibitor 2; Cytokine response modifier A, a serpin inhbitor of caspase-1 and granzyme B.; CrmA or CPXV207 protein; Cytokine response modifier protein A; Hemorrhage-inducing 38 kDa protein; ICE inhibitor
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Gene name
CRMA
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Other gene names
CrmA; CRMA; CPXV207; SPI-2; Serp-2; Serpin-2
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General description
Serine proteinase inhibitor 2 (CRMA) is a recombinant protein expressed in Yeast . The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.
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Product category
Recombinant Proteins
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Expression system
Yeast
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Available also expressed in
E Coli ; Yeast ; Baculovirus ; Mammalian Cell
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Purity
Greater than 90% (determined by SDS-PAGE)
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Form
Lyophilized protein
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Storage
This protein can be stored at -20 degrees Celsius. For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius. Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains.
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Applications
This protein can be used as a positive control for applications such as ELISA, IFA, RIA, Western Blot, etc.
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Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+
3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.
