Arabidopsis thaliana Protein LSD1 (LSD1) -Baculovirus

  • Catalog number
    GEN1217282.Baculovirus
  • Price
    Please ask
  • Size
    100ug
  • Long name
    Recombinant Arabidopsis thaliana Protein LSD1 (LSD1)
  • Alternative names
    zinc finger protein LSD1; Protein LSD1; zinc finger protein LSD1; Protein CHILLING SENSITIVE 4; Protein LESION SIMULATING DISEASE 1; AtLSD1; Putative zinc finger LSD1
  • Gene name
    LSD1
  • Other gene names
    AT4G20380; LSD1; F9F13.30; F9F13_30; LESION SIMULATING DISEASE; LSD1; CHS4; AtLSD1
  • General description
    Protein LSD1 (LSD1) is a recombinant protein expressed in Baculovirus . The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.
  • Product category
    Recombinant Proteins
  • Expression system
    Baculovirus
  • Available also expressed in
    E Coli ; Yeast ; Baculovirus ; Mammalian Cell
  • Purity
    Greater than 90% (determined by SDS-PAGE)
  • Form
    Lyophilized protein
  • Storage
    This protein can be stored at -20 degrees Celsius. For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius. Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains.
  • Applications
    This protein can be used as a positive control for applications such as ELISA, IFA, RIA, Western Blot, etc.
  • Gene
    Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
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