Vascular Endothelial Cadherin (VE-Cadherin, CD144) (FITC)

• Catalog number
  MBS613914
• Price
  Please ask
• Size
  100 Tests

• Alternative name1
  Anti-Vascular Endothelial Cadherin (VE-Cadherin, CD144) (FITC)
• Alternative name2
  Vascular Endothelial Cadherin (VE-Cadherin, CD144) (FITC)
• Alternative name3
  Vascular Endothelial Cadherin (VE-Cadherin, CD144) (FITC)
• Alternative name4
  Vascular Endothelial Cadherin
• Alternative name5
  Anti -Vascular Endothelial Cadherin (VE-Cadherin, CD144) (FITC)
• Other names
  vascular endothelial cadherin; Cadherin-5; cadherin-5; 7B4 antigen; VE-cadherin; cd144 antigen; OTTHUMP00000174777; endothelial-specific cadherin; vascular endothelial cadherin; cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin 5, type 2 (vascular endothelium); 7B4 antigen; Vascular endothelial cadherin
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  CDH5; CDH5; 7B4; CD144; FLJ17376; N/A
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  IgG
• Clone
  Polyclonal antibody
• Host organism
  Host: Rabbit; Source: Human
• Species reactivity
  Bovine, Human, Mouse, Rat
• Specificity and cross reactivity
  Recognizes human VE-cadherin. Species Crossreactivity: mouse, rat and bovine
• Purification method
  Affinity Purified by immunoaffinity chromatography
• Form Appearance
  Supplied as a liquid in 50mM Tris, pH 7.3, 100mM sodium chloride, 1% BSA, 0.02% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
• Concentration
  N/A
• Storage and shipping
  Store at 4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
• Tested for
  Flow Cytometry (FC/FACS)
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  This MBS Polyclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MBS Polyclonals FITC is highly sensitive to pH extremes.
• Conjugation
  Anti-FITC Antibody

• Gene target
  Vascular   Endothelial   Cadherin   VE-Cadherin   CD144  
• Gene symbol
  JAM2, CDH5
• Short name
  Vascular Endothelial Cadherin (VE-Cadherin, CD144) (FITC)
• Technique
  FITC, Fluorescein
• Label
  FITC
• Alternative name
  Vascular Endothelial Cadherin (VE-Cadherin, CD144) (fluorecein)
• Alternative technique
  fluorescine
• Tissue
  vascular

Gene info

• Identity
  HGNC:14686
• Gene
  JAM2
• Long gene name
  junctional adhesion molecule 2
• Synonyms gene
  • C21orf43
• Synonyms
  • VE-JAM
  • JAM-B
  • JAMB
  • CD322
• GenBank acession
  • AF255910
• Locus
  21q21.3
• Discovery year
  2001-04-25
• Entrez gene record
  58494
• Pubmed identfication
  • 10779521
  • 10945976
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • I-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000078441

Gene info

• Identity
  HGNC:1764
• Gene
  CDH5
• Long gene name
  cadherin 5
• Synonyms gene name
  • cadherin 5, type 2, VE-cadherin (vascular epithelium)
  • cadherin 5, type 2 (vascular endothelium)
• Synonyms
  • 7B4
  • CD144
• Synonyms name
  • VE-cadherin
• GenBank acession
  • X79981
• Locus
  16q21
• Discovery year
  1992-11-20
• Entrez gene record
  1003
• Pubmed identfication
  • 2059658
• RefSeq identity
  • NM_001795
• Classification
  • Type II classical cadherins
  • CD molecules
• VEGA ID
  OTTHUMG00000137495

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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