TBLR1 (TBL1XR1, IRA1, C21, DC42, TBL1-related protein 1, transducin (beta)-like 1 X-linked receptor 1) Antibody
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Catalog numberMBS610091
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PricePlease ask
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Size100ug
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Alternative name1Anti-TBLR1 (TBL1XR1, IRA1, C21, DC42, TBL1-related protein 1, transducin (beta)-like 1 X-linked receptor 1)
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Alternative name2TBLR1 (TBL1XR1, IRA1, C21, DC42, TBL1-related protein 1, transducin (beta)-like 1 X-linked receptor 1)
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Alternative name3TBLR1 (TBL1XR1, IRA1, C21, DC42, TBL1-related protein 1, transducin (beta)-like 1 X-linked receptor 1)
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Alternative name4TBLR1
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Alternative name5Anti -TBLR1 (TBL1XR1, IRA1, C21, DC42, TBL1-related protein 1, transducin (beta)-like 1 X-linked receptor 1)
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Other namesTransducin (beta)-like 1 X-linked receptor 1; F-box-like/WD repeat-containing protein TBL1XR1; F-box-like/WD repeat-containing protein TBL1XR1; OTTHUMP00000211531; OTTHUMP00000211535; TBL1-related protein 1; transducin beta-like 1X-related protein 1; nuclear receptor co-repressor/HDAC3 complex subunit; nuclear receptor corepressor/HDAC3 complex subunit TBLR1; transducin (beta)-like 1 X-linked receptor 1; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesTBL1XR1; TBL1XR1; C21; DC42; IRA1; TBLR1; FLJ12894; IRA1; TBLR1
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypeIgG
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ClonePolyclonal antibody
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Host organismHost: Rabbit; Source: Human
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Species reactivityHuman, Mouse, Rat
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Specificity and cross reactivityChromatin organization plays a fundamental role in regulating transcription in eukaryotic cells. The nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid homone receptors (SMRT) play a role in diverse transcriptional repression pathways. N-CoR and SMRT each exist in large protein complexes, and are thought to mediate repression, at least in part, by their ability to recruit histone deacetylases to generate repressive chromatin. HDAC3 is the main HDAC that associates with N-CoR and SMRT complexes, and its presence is thought to be essential for repression. TBLR1 is a WD-40 repeat protein that also associates with N-CoR and SMRT complexes. Although TBLR1 is thought to be a core component of both the N-CoR and SMRT complexes, its role in these complexes remains to be elucidated.
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Purification methodPurified
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Form AppearanceSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
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ConcentrationN/A
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Storage and shippingStore at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze productone should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested forWestern Blot (WB)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesIf you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional descriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translationanticorps
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Gene target
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Gene symbolTBL1XR1, TBL1Y, TBL1X, TBL1XR1-AS1, PSMG1
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Short nameTBLR1 (TBL1XR1, IRA1, C21, DC42, TBL1- protein 1, transducin (beta)-like 1 X-linked receptor 1) Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameTBLR1 (TBL1XR1, IRA1, C21, DC42, TBL1-related protein 1, transducin (b)-like 1 X-linked receptor 1) (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameTBL1X receptor 1
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Synonyms gene name
- transducin (beta)-like 1X-linked receptor 1
- transducin beta like 1 X-linked receptor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-08-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
- NCoR/SMRT transcriptional repression complex subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametransducin beta like 1 Y-linked
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Synonyms gene name
- transducin (beta)-like 1, Y-linked
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-05-22
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Entrez gene record
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RefSeq identity
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Classification
- WD repeat domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametransducin beta like 1 X-linked
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Synonyms gene
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Synonyms gene name
- transducin (beta)-like 1
- transducin (beta)-like 1X-linked
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
- NCoR/SMRT transcriptional repression complex subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTBL1XR1 antisense RNA 1
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Synonyms gene name
- TBL1XR1 antisense RNA 1 (non-protein coding)
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Locus
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Discovery year2011-07-25
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameproteasome assembly chaperone 1
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Synonyms gene
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Synonyms gene name
- Down syndrome critical region gene 2
- proteasome (prosome, macropain) assembly chaperone 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-09-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
