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Alternative name1
Anti-SHARP (SMART/HDAC1 Associated Repressor Protein, SMART/HDAC1-associated Repressor Protein, KIAA0929, Msx2-interacting Nuclear Target (MINT) Homolog, MINT, Msx2-interacting Protein, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul
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Alternative name2
SHARP (SMART/HDAC1 Associated Repressor Protein, SMART/HDAC1-associated Repressor Protein, KIAA0929, Msx2-interacting Nuclear Target (MINT) Homolog, MINT, Msx2-interacting Protein, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul
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Alternative name3
SHARP (SMART/HDAC1 Associated Repressor Protein, SMART/HDAC1-associated Repressor Protein, KIAA0929, Msx2-interacting Nuclear Target (MINT) Homolog, MINT, Msx2-interacting Protein, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul
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Alternative name4
SHARP
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Alternative name5
Anti -SHARP (SMART/HDAC1 Associated Repressor Protein, SMART/HDAC1-associated Repressor Protein, KIAA0929, Msx2-interacting Nuclear Target (MINT) Homolog, MINT, Msx2-interacting Protein, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul
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Other names
Small histidine-alanine-rich protein; N/A
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
N/A
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
N/A
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Clone
Polyclonal antibody
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Host organism
Host: Rabbit; Source: Human
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Species reactivity
Human
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Specificity and cross reactivity
Species Crossreactivity: Human.
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Purification method
Affinity Purified by immunoaffinity chromatography.
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Form Appearance
Tris-citrate/phosphate buffer, pH 7 to 8
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Concentration
N/A
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Storage and shipping
Store at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested for
Western Blot (WB), Immunoprecipitation (IP)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Gene target
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Gene symbol
SPEN, HDAC1, CISD3, BHLHE41
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Short name
SHARP (SMART/HDAC1 Associated Repressor Protein, SMART/HDAC1-associated Repressor Protein, KIAA0929, Msx2-interacting (MINT) Homolog, MINT, Msx2-interacting Protein, Receptor Transcription Cofactor Spen Homolog Transcriptional Regul
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Alternative name
SHARP (SMART/histone deacetylase 1 Associated Repressor Protein, SMART/histone deacetylase 1-associated Repressor Protein, KIAA0929, msh homeobox 2-interacting Nuclear Target (MINT) Homolog, MINT, msh homeobox 2-interacting Protein, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul
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Alternative to gene target
msh homeobox 2, CRS2 and FPP and HOX8 and MSH and PFM and PFM1, MSX2 and IDBG-58312 and ENSG00000120149 and 4488, transcription regulatory region DNA binding, nuclei, Msx2 and IDBG-153222 and ENSMUSG00000021469 and 17702, MSX2 and IDBG-628518 and ENSBTAG00000013873 and 540230
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