PDCD4, phosphorylated (Ser457) (Programmed Cell Death 4, Neoplastic Transformation Inhibitor, H731, MGC33046, MGC33047, Nuclear Antigen H731, OTTHUMP00000020483, Protein 197/15a, RP11 348N5.4)
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Catalog numberMBS618247
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PricePlease ask
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Size100ug
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Alternative name1Anti-PDCD4, phosphorylated (Ser457) (Programmed Cell Death 4, Neoplastic Transformation Inhibitor, H731, MGC33046, MGC33047, Nuclear Antigen H731, OTTHUMP00000020483, Protein 197/15a, RP11 348N5.4)
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Alternative name2PDCD4, phosphorylated (Ser457) (Programmed Cell Death 4, Neoplastic Transformation Inhibitor, H731, MGC33046, MGC33047, Nuclear Antigen H731, OTTHUMP00000020483, Protein 197/15a, RP11 348N5.4)
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Alternative name3PDCD4, phosphorylated (Ser457) (Programmed Cell Death 4, Neoplastic Transformation Inhibitor, H731, MGC33046, MGC33047, Nuclear Antigen H731, OTTHUMP00000020483, Protein 197/15a, RP11 348N5.4)
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Alternative name4PDCD4
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Alternative name5Anti -PDCD4, phosphorylated (Ser457) (Programmed Cell Death 4, Neoplastic Transformation Inhibitor, H731, MGC33046, MGC33047, Nuclear Antigen H731, OTTHUMP00000020483, Protein 197/15a, RP11 348N5.4)
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Other namesprogrammed cell death protein 4 isoform 2; Programmed cell death protein 4; programmed cell death protein 4; protein 197/15a; OTTHUMP00000020483; nuclear antigen H731; neoplastic transformation inhibitor protein; programmed cell death 4 (neoplastic transformation inhibitor); Neoplastic transformation inhibitor protein; Nuclear antigen H731-like; Protein 197/15a
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesPDCD4; PDCD4; H731; MGC33046; MGC33047; H731
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypeN/A
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ClonePolyclonal antibody
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Host organismHost: Rabbit; Source: Human
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Species reactivityHuman, Mouse, Rat, Xenopus
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Specificity and cross reactivityThis product was affinity purified from monospecific antiserum by immunoaffinity chromatography using phospho-peptide coupled to agarose beads followed by solid phase adsorption against nonphospho-peptide. This antibody is specific for human Pdcd4 protein phosphorylated at Ser457. A BLAST analysis was used to suggest crossreactivity with Pdcd4 from human, mouse, rat and Xenopus based on 100% homology with the immunizing sequence. Cross-reactivity with Pdcd4 from other sources has not been determined. Species Crossreactivity: Reactive with human, mouse, rat and xenopus, based on 100% homology with immunogen.
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Purification methodAffinity Purified by immunoaffinity chromatography.
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Form Appearance0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
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ConcentrationN/A
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Storage and shippingStore at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested forELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional descriptionAntigens are peptides or recombinant or native dependent on the production method. For cells, cell lines and tissues in culture till half confluency. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolPDCD4, PDCD4-AS1, ATP2C2-AS1, LINC02231, LINC02866, LINC02562, LINC02932, LINC01511, LINC02232, LINC02179
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Short namePDCD4, phosphorylated (Ser457) (Programmed Death 4, Neoplastic Transformation Inhibitor, H731, MGC33046, MGC33047, Antigen H731, OTTHUMP00000020483, Protein 197/15a, RP11 348N5 4)
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Techniqueantigen, antigenes
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Alternative nameprogrammed cellular death 4 (neoplastic transformation inhibitor), phosphorylated (Ser457) (Programmed cellular Death 4, Neoplastic Transformation suppressor, H731, MGC33046, MGC33047, Nuclear protein H731, OTTHUMP00000020483, Protein 197/15a, RP11 348N5.4)
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Alternative techniqueantigenes
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Alternative to gene targetprogrammed cell death 4 (neoplastic transformation inhibitor), PDCD4 and IDBG-89535 and ENSG00000150593 and 100616113,27250, protein binding, nuclei, Pdcd4 and IDBG-176913 and ENSMUSG00000024975 and 18569, PDCD4 and IDBG-639738 and ENSBTAG00000019434 and 506724
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Tissuecell
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Gene info
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Identity
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Gene
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Long gene nameprogrammed cell death 4
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Synonyms gene name
- programmed cell death 4 (neoplastic transformation inhibitor)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-05-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePDCD4 antisense RNA 1
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Locus
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Discovery year2013-03-11
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Entrez gene record
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameATP2C2 antisense RNA 1
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Synonyms
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Locus
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Discovery year2017-03-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene namelong intergenic non-protein coding RNA 2231
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Synonyms
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Locus
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Discovery year2017-02-09
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Pubmed identfication
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Classification
- Long intergenic non-protein coding RNAs
Gene info
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Identity
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Gene
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Long gene namelong intergenic non-protein coding RNA 2866
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Synonyms
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Locus
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Discovery year2019-09-18
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Entrez gene record
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Pubmed identfication
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Classification
- Long intergenic non-protein coding RNAs
Gene info
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Identity
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Gene
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Long gene namelong intergenic non-protein coding RNA 2562
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Synonyms
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Locus
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Discovery year2017-06-16
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Pubmed identfication
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Classification
- Long intergenic non-protein coding RNAs
Gene info
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Identity
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Gene
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Long gene namelong intergenic non-protein coding RNA 2932
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Synonyms
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Locus
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Discovery year2021-09-22
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Entrez gene record
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Pubmed identfication
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Classification
- Long intergenic non-protein coding RNAs
Gene info
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Identity
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Gene
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Long gene namelong intergenic non-protein coding RNA 1511
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Synonyms
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GenBank acession
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Locus
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Discovery year2014-08-06
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Entrez gene record
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Pubmed identfication
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Classification
- Long intergenic non-protein coding RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelong intergenic non-protein coding RNA 2232
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Synonyms
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Locus
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Discovery year2017-02-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Long intergenic non-protein coding RNAs
Gene info
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Identity
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Gene
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Long gene namelong intergenic non-protein coding RNA 2179
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Synonyms
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Locus
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Discovery year2017-01-11
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Entrez gene record
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Pubmed identfication
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Classification
- Long intergenic non-protein coding RNAs
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VEGA ID