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Alternative name1
Anti-Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
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Alternative name2
Rabbit PAb (IgG) to Human CASP1 / Caspase 1
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Alternative name3
Lapin Polyclonal (IgG) to Homo sapiens CASP1 / Caspase 1
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Alternative name4
CASP1 / Caspase 1
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Alternative name5
Anti-CASP1 / Caspase 1 Antibody (FITC) IHC-plus; CASP1; Caspase-1; CASP-1; CASP1 nirs variant 1; Caspase 1; ICE; ICE-like protease; IL-1 beta-converting enzyme; IL-1BC; IL1BC; IL1BCE; p45; IL1B-convertase; Interleukin-1 beta convertase; Human CASP1; Caspase 1
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Other names
caspase-1 isoform beta; Caspase-1; caspase-1; IL1B-convertase; CASP1 nirs variant 1; IL-1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); caspase 1, apoptosis-related cysteine peptidase; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45Cleaved into the following 2 chains:Caspase-1 subunit p20; Caspase-1 subunit p10
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Gene name
CASP1
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Gene name synonims
N/A
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Other gene names
CASP1; CASP1; ICE; P45; IL1BC; IL1BC; IL1BCE; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
IgG
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Clone
Polyclonal antibody
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Host organism
Rabbit
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Species reactivity
Human
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Specificity and cross reactivity
Human CASP1 / Caspase 1
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Purification method
Caprylic acid and ammonium sulfate precipitation
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Form Appearance
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
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Concentration
0.25 mg/ml
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Storage and shipping
Aliquot and store productone should be stored at -20 degrees Celsius. or -80 degree C. Avoid freeze-thaw cycles.
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Tested for
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.