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Alternative name1
Anti-Muscarinic Receptor M2, aa457-466 (Cholinergic Muscarinic Receptor M2, Chrm2)
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Alternative name2
Muscarinic Receptor M2, aa457-466 (Cholinergic Muscarinic Receptor M2, Chrm2)
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Alternative name3
Muscarinic Receptor M2, aa457-466 (Cholinergic Muscarinic Receptor M2, Chrm2)
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Alternative name4
Muscarinic Receptor M2, aa457-466
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Alternative name5
Anti -Muscarinic Receptor M2, aa457-466 (Cholinergic Muscarinic Receptor M2, Chrm2)
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Other names
muscarinic acetylcholine receptor M2; Muscarinic acetylcholine receptor M2; muscarinic acetylcholine receptor M2; 7TM receptor; OTTHUMP00000208393; OTTHUMP00000208394; OTTHUMP00000208395; OTTHUMP00000208396; muscarinic M2 receptor; cholinergic receptor, muscarinic 2, isoform a; cholinergic receptor, muscarinic 2; N/A
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
CHRM2; CHRM2; HM2; FLJ43243; MGC120006; MGC120007; N/A
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
IgG
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Clone
Polyclonal antibody
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Host organism
Host: Rabbit; Source: Human
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Species reactivity
Human
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Specificity and cross reactivity
Shown to be specific for the COOH terminal of the M2 receptor. M2 Muscarinic Receptor (457-466) 100% M2 Muscarinic Receptor 50% M1 Muscarinic Receptor (451-460) 0% M3 Muscarinic Receptor (580-589 0% M3 Muscarinic Receptor 0% M4 Muscarinic Receptor (469-478) 0% M4 Muscarinic Receptor 0% M5 Muscarinic Receptor (519-531) 0% M5 Muscarinic Receptor 0%
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Purification method
Purified by ammonium sulfate precipitation, dialysis and chromatography.
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Form Appearance
Supplied as a liquid in PBS, pH 7.2, 10mg/ml BSA, 40% glycerol.
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Concentration
N/A
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Storage and shipping
Store at 4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested for
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translation
anticorps