MED4, CT (Mediator of RNA Polymerase II Transcription Subunit 4, Mediator Complex Subunit 4, Activator-recruited Cofactor 36kD Component, ARC36, DRIP36, FLJ10956, HSPC126, RP11-90M2.2, TRAP/SMCC/PC2 Subunit p36 Subunit, TRAP36, Vitamin D3 Receptor-interac Antibody

• Catalog number
  MBS647816
• Price
  Please ask
• Size
  50ug

• Alternative name1
  Anti-MED4, CT (Mediator of RNA Polymerase II Transcription Subunit 4, Mediator Complex Subunit 4, Activator-recruited Cofactor 36kD Component, ARC36, DRIP36, FLJ10956, HSPC126, RP11-90M2.2, TRAP/SMCC/PC2 Subunit p36 Subunit, TRAP36, Vitamin D3 Receptor-interac
• Alternative name2
  MED4, CT (Mediator of RNA Polymerase II Transcription Subunit 4, Mediator Complex Subunit 4, Activator-recruited Cofactor 36kD Component, ARC36, DRIP36, FLJ10956, HSPC126, RP11-90M2.2, TRAP/SMCC/PC2 Subunit p36 Subunit, TRAP36, Vitamin D3 Receptor-interac
• Alternative name3
  MED4, CT (Mediator of RNA Polymerase II Transcription Subunit 4, Mediator Complex Subunit 4, Activator-recruited Cofactor 36kD Component, ARC36, DRIP36, FLJ10956, HSPC126, RP11-90M2.2, TRAP/SMCC/PC2 Subunit p36 Subunit, TRAP36, Vitamin D3 Receptor-interac
• Alternative name4
  MED4
• Alternative name5
  Anti -MED4, CT (Mediator of RNA Polymerase II Transcription Subunit 4, Mediator Complex Subunit 4, Activator-recruited Cofactor 36kD Component, ARC36, DRIP36, FLJ10956, HSPC126, RP11-90M2.2, TRAP/SMCC/PC2 Subunit p36 Subunit, TRAP36, Vitamin D3 Receptor-interac
• Other names
  Med4 protein; Mediator of RNA polymerase II transcription subunit 4; mediator of RNA polymerase II transcription subunit 4; mediator complex subunit 4; Mediator complex subunit 4
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  med4; med4; zgc:110646; N/A
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  N/A
• Clone
  Polyclonal antibody
• Host organism
  Host: Rabbit; Source: Human
• Species reactivity
  Human
• Specificity and cross reactivity
  Recognizes human MED4. Species sequence homology: Mouse, rat.
• Purification method
  Affinity Purified by immunoaffinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, 0.02% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store at 4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested for
  Western Blot (WB), Immunohistochemistry (IHC)
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
• French translation
  anticorps

• Gene target
  MED4   Mediator   RNA   Polymerase   Transcription   Subunit   Mediator   Complex   Subunit   Activator-recruited   Cofactor   36kD   Component   ARC36   DRIP36   FLJ10956   HSPC126   RP11-90M2   TRAP/SMCC/PC2   Subunit   p36   Subunit   TRAP36   Vitamin   Receptor-interac  
• Gene symbol
  MED4, MED4-AS1, NUDT15, ACP5, CBX4, PCSK2, CNN1, PKD2, TGFBRAP1, TAGLN
• Short name
  MED4, CT (Mediator of RNA Polymerase II Transcription Subunit 4, Mediator Complex Subunit 4, Activator-recruited Cofactor 36kD Component, ARC36, DRIP36, FLJ10956, HSPC126, RP11-90M2 2, TRAP/SMCC/PC2 Subunit p36 Subunit, TRAP36, Vitamin D3 Receptor-interac Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for, RNAs are to store at -70 C
• Alternative name
  MED4, CT (Mediator on RNA polymerizing enzyme II Transcription functionnal sequence 4, Mediator aggregate functionnal sequence 4, Activator-recruited Cofactor 36kD Component, ARC36, DRIP36, FLJ10956, HSPC126, RP11-90M2.2, TRAP/SMCC/PC2 functionnal sequence p36 functionnal sequence, TRAP36, Vitamin D3 Receptor-interac (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17903
• Gene
  MED4
• Long gene name
  mediator complex subunit 4
• Synonyms gene
  • VDRIP
• Synonyms gene name
  • vitamin D receptor interacting protein
  • mediator of RNA polymerase II transcription, subunit 4 homolog (S. cerevisiae)
• Synonyms
  • HSPC126
  • DRIP36
  • TRAP36
• GenBank acession
  • AF161475
• Locus
  13q14.2
• Discovery year
  2003-05-23
• Entrez gene record
  29079
• Pubmed identfication
  • 10235266
  • 11042152
• RefSeq identity
  • NM_014166
• Classification
  • Mediator complex
• VEGA ID
  OTTHUMG00000016891

Gene info

• Identity
  HGNC:39213
• Gene
  MED4-AS1
• Long gene name
  MED4 antisense RNA 1
• Synonyms gene
  • MED4-AS
• Synonyms gene name
  • MED4 antisense RNA (non-protein coding)
  • MED4 antisense RNA 1 (non-protein coding)
• Locus
  13q14.2
• Discovery year
  2010-11-23
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000016893

Gene info

• Identity
  HGNC:23063
• Gene
  NUDT15
• Long gene name
  nudix hydrolase 15
• Synonyms gene name
  • nudix (nucleoside diphosphate linked moiety X)-type motif 15
• Synonyms
  • MTH2
  • FLJ10956
• Locus
  13q14.2
• Discovery year
  2003-12-22
• Entrez gene record
  55270
• Pubmed identfication
  • 12767940
  • 25108385
• RefSeq identity
  • NM_018283
• Classification
  • Nudix hydrolase family
• VEGA ID
  OTTHUMG00000016890
• Locus Specific Databases
  • PharmVar Pharmacogene Variation Consortium

Gene info

• Identity
  HGNC:124
• Gene
  ACP5
• Long gene name
  acid phosphatase 5, tartrate resistant
• Synonyms
  • TRAP
  • HPAP
• Synonyms name
  • tartrate-resistant acid phosphatase
  • human purple acid phosphatase
• GenBank acession
  • X14618
• Locus
  19p13.2
• Discovery year
  1989-02-23
• Entrez gene record
  54
• Pubmed identfication
  • 8449511
  • 2338077
• Classification
  • Acid phosphatases
• VEGA ID
  OTTHUMG00000182036
• Locus Specific Databases
  • LRG_1218

Gene info

• Identity
  HGNC:1554
• Gene
  CBX4
• Long gene name
  chromobox 4
• Synonyms gene name
  • chromobox homolog 4 (Drosophila Pc class)
  • chromobox homolog 4
• Synonyms
  • hPC2
  • PC2
  • NBP16
• Synonyms name
  • NS5ATP1-binding protein 16
  • Pc class 2 homolog (Drosophila)
• GenBank acession
  • AF013956
• Locus
  17q25.3
• Discovery year
  1998-10-20
• Entrez gene record
  8535
• Pubmed identfication
  • 9315667
• RefSeq identity
  • NM_003655
• Classification
  • Chromobox family
• VEGA ID
  OTTHUMG00000150415

Gene info

• Identity
  HGNC:8744
• Gene
  PCSK2
• Long gene name
  proprotein convertase subtilisin/kexin type 2
• Synonyms gene
  • NEC2
• Synonyms
  • PC2
  • SPC2
• Synonyms name
  • neuroendocrine convertase 2
  • KEX2-like endoprotease 2
• GenBank acession
  • AK312341
• Locus
  20p12.1
• Discovery year
  1991-06-07
• Entrez gene record
  5126
• Pubmed identfication
  • 1765368
• RefSeq identity
  • NM_002594
• Classification
  • Proprotein convertase subtilisin/kexin family
• VEGA ID
  OTTHUMG00000031941

Gene info

• Identity
  HGNC:2155
• Gene
  CNN1
• Long gene name
  calponin 1
• Synonyms gene name
  • calponin 1, basic, smooth muscle
• Synonyms
  • SMCC
  • Sm-Calp
• GenBank acession
  • U37019
• Locus
  19p13.2
• Discovery year
  1996-08-16
• Entrez gene record
  1264
• Pubmed identfication
  • 8526917
  • 9332369
• RefSeq identity
  • NM_001299
• VEGA ID
  OTTHUMG00000182033

Gene info

• Identity
  HGNC:9009
• Gene
  PKD2
• Long gene name
  polycystin 2, transient receptor potential cation channel
• Synonyms gene name
  • polycystic kidney disease 2 (autosomal dominant)
• Synonyms
  • PKD4
  • PC2
  • Pc-2
  • TRPP2
• Synonyms name
  • transient receptor potential cation channel, subfamily P, member 2
• GenBank acession
  • U50928
• Locus
  4q22.1
• Discovery year
  1988-08-07
• Entrez gene record
  5311
• Pubmed identfication
  • 8298643
• RefSeq identity
  • NM_000297
• Classification
  • Transient receptor potential cation channels
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000160982
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:16836
• Gene
  TGFBRAP1
• Long gene name
  transforming growth factor beta receptor associated protein 1
• Synonyms gene name
  • transforming growth factor, beta receptor associated protein 1
• Synonyms
  • TRAP-1
  • TRAP1
  • VPS3
• Synonyms name
  • VPS3 CORVET complex subunit
• GenBank acession
  • AF022795
• Locus
  2q12.1-q12.2
• Discovery year
  2003-02-11
• Entrez gene record
  9392
• Pubmed identfication
  • 9545258
  • 11278302
  • 26463206
• RefSeq identity
  • NM_004257
• Classification
  • CORVET complex
• VEGA ID
  OTTHUMG00000130809

Gene info

• Identity
  HGNC:11553
• Gene
  TAGLN
• Long gene name
  transgelin
• Synonyms
  • SM22
  • WS3-10
  • TAGLN1
  • SMCC
  • DKFZp686P11128
• Synonyms name
  • SM22-alpha
  • transgelin variant 2
• GenBank acession
  • M95787
• Locus
  11q23.3
• Discovery year
  1998-01-16
• Entrez gene record
  6876
• Pubmed identfication
  • 8117285
  • 1520290
• RefSeq identity
  • NM_001001522
• VEGA ID
  OTTHUMG00000167067

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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