-
Alternative name1
Anti-GOAT ANTI HUMAN NALP3 (C-TERMINAL)
-
Alternative name2
Caprine ANTI HUMAN NALP3 (C-TERMINAL)
-
Alternative name3
Caprinae ANTI Homo sapiens NALP3 (C-TERMINAL)
-
Alternative name4
NALP3
-
Alternative name5
N/A
-
Other names
NACHT, LRR and PYD domains-containing protein 3 isoform a; NACHT, LRR and PYD domains-containing protein 3; NACHT, LRR and PYD domains-containing protein 3; cryopyrin; caterpiller protein 1.1; PYRIN-containing APAF1-like protein 1; NACHT, LRR and PYD containing protein 3; cold autoinflammatory syndrome 1 protein; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3; NLR family, pyrin domain containing 3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1
-
Gene name
NALP3
-
Gene name synonims
N/A
-
Other gene names
NLRP3; NLRP3; AII; AVP; FCU; MWS; FCAS; CIAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL; C1orf7; CIAS1; NALP3; PYPAF1; CLR1.1
-
Category
Antibodies
-
Clonality
Polyclonal
-
Immunoglobulin isotype
Polyclonal IgG
-
Clone
Polyclonal antibody
-
Host organism
Goat
-
Species reactivity
Human
-
Specificity and cross reactivity
NALP3 This item recognises human NACHT, LRR and PYD domains-containing protein 3 (NALP3), a cytoplasmic protein belonging to the NLRP family. _x000D_NALP3 is involved in inflammation and immune response. Research indicates that NALP3 may function as an activator of NF-kappaB signalling and play a role in the regulation of inflammation and apoptosis. _x000D_Mutations in the NALP3 gene have been associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). _x000D_NALP3 is strongly expressed in polymorphonuclear cells, osteoblasts and chondrocytes, NALP3 can also be detected in non-keratinizing epithelia of oropharynx, esophagus and ectocervix and in the urothelial layer of the bladder.
-
Purification method
N/A
-
Form Appearance
Purified (Purified IgG - liquid)
-
Concentration
IgG concentration 500ug/1000ul
-
Storage and shipping
Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
-
Tested for
ELISA (EIA), Immunohistology - Paraffin (IHC)
-
Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
-
Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
-
Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
-
Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Latin name
Capra aegagrus hircus
-
French translation
anticorps
