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Alternative name1
Anti-RABBIT ANTI RAT GABA TRANSPORTER 3 (C-TERMINAL)
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Alternative name2
RABBIT ANTI RAT GABA TRANSPORTER 3 (C-TERMINAL)
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Alternative name3
Lapin ANTI Rattus norvegicus GABA TRANSPORTER 3 (C-TERMINAL)
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Alternative name4
GABA TRANSPORTER 3
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Alternative name5
N/A
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Other names
sodium- and chloride-dependent GABA transporter 3; Sodium- and chloride-dependent GABA transporter 3; sodium- and chloride-dependent GABA transporter 3; GAT-3; GABA transporter GAT-3; solute carrier family 6 member 11; solute carrier family 6 (neurotransmitter transporter, GABA), member 11; Solute carrier family 6 member 11
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
Slc6a11; Slc6a11; Gat3; Gabt4; Gabt3; Gat-3; Gat-b; GAT-3
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
Polyclonal IgG
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Clone
Polyclonal antibody
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Host organism
Rabbit
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Species reactivity
Rat
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Specificity and cross reactivity
GABA TRANSPORTER 3 This item recognises an epitope within the C-terminal region (CT) of rat GABA transporter 3, otherwise known as GAT-3, a 67kDa high-affinity Na+/Cl- dependent plasma membrane transporter and member of the sodium: neurotransmitter symporter (SNF) family, expressed in the cerebral cortex and retina. _x000D__x000D_GAT-3 is one of a group of proteins involved in the regulation of GABAergic synaptic neurotransmission, through the uptake and release of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter of the mammalian central nervous system, which must be maintained at the correct level to ensure successful synaptic transmission. Further GABA transporter genes identified are GAT-1, GAT-2 and GAT-4, and many studies have linked neurotransmitter transporters with neurological disorders, including epilepsy and ischemia.
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Purification method
N/A
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Form Appearance
Purified (Purified IgG - liquid)
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Concentration
N/A
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Storage and shipping
Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of dispatch.
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Tested for
Western Blot (WB)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
