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Alternative name1
Anti-RABBIT ANTI NFkB p65
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Alternative name2
RABBIT ANTI NFkB p65
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Alternative name3
Lapin ANTI NFkB p65
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Alternative name4
NFkB p65
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Alternative name5
N/A
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Other names
transcription factor p65 isoform 2; Transcription factor p65; transcription factor p65; NF-kappa-B p65delta3; nuclear factor NF-kappa-B p65 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; v-rel reticuloendotheliosis viral oncogene homolog A (avian); Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
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Gene name
NFkB p65
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Gene name synonims
N/A
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Other gene names
RELA; RELA; p65; NFKB3; NFKB3
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
Polyclonal IgG
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Clone
Polyclonal antibody
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Host organism
Rabbit
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Species reactivity
Human
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Specificity and cross reactivity
NFkB p65 This item is reactive with human NFkB p65 subunit (Rel A). In a gel supershift assay this antibody was found to be active against all p65 containing human, mouse or rat NFkB complexes using 0.5ul to 1.0ul per assay. The specific binding of this antibody to the NFkB p65 subunit can be blocked using the NFkB p65 control peptide.
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Purification method
N/A
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Form Appearance
Serum (Serum - liquid)
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Concentration
N/A
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Storage and shipping
Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. productone should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
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Tested for
Gel Super Shift Assay (GS), Western Blot (WB), Immunofluorescence (IF), ELISA (EIA), Immunoprecipitation (IP)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Gene
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
