Anti-MOUSE ST2 (N-TERMINAL)

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  • Catalog number
    MBS221876
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  • Size
    100ug
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  • Alternative name1
    Anti-RABBIT ANTI MOUSE ST2 (N-TERMINAL)
  • Alternative name2
    RABBIT ANTI Murine ST2 (N-TERMINAL)
  • Alternative name3
    Lapin ANTI Mus musculus ST2 (N-TERMINAL)
  • Alternative name4
    ST2
  • Alternative name5
    N/A
  • Other names
    interleukin-1 receptor-like 1 isoform a; Interleukin-1 receptor-like 1; interleukin-1 receptor-like 1; T1; protein T1; lymphocyte antigen 84; interleukin 1 receptor-like 1; Lymphocyte antigen 84; Protein ST2; Protein T1
  • Gene name
    ST2
  • Gene name synonims
    N/A
  • Other gene names
    Il1rl1; Il1rl1; T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1; Ly84; St2; Ste2
  • Category
    Antibodies
  • Clonality
    Polyclonal
  • Immunoglobulin isotype
    Polyclonal IgG
  • Clone
    Polyclonal antibody
  • Host organism
    Rabbit
  • Species reactivity
    Mouse
  • Specificity and cross reactivity
    ST2 This item recognises an epitope within the N-terminal region (NT) of mouse ST2, a member of the Toll-interleukin 1 receptor (TIR) superfamily, expressed by mast cells and TH2 helper cells, but not by TH1 effector cells. The majority of TIR superfamily members, which includes the Interleukin-1 receptor (IL-1R1), Toll-like receptors (TLRs) and the cytosolic adaptor proteins MyD88, TIRAP, Trif and TRAM, initiate innate immunity through the ultimate activation of the transcription factor NF-kappaB and are inducers of the inflammatory response. In contrast ST2, which itself is unable to activate NF-kappaB, has been identified as a negative regulator of IL-1R1 and TLR4 signaling by sequestering MyD88 and TIRAP in line with its role as a crucial receptor in TH2-cell mediated responses
  • Purification method
    N/A
  • Form Appearance
    Purified (Purified IgG - liquid)
  • Concentration
    IgG concentration 1.0mg/ml
  • Storage and shipping
    Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
  • Tested for
    Western Blot (WB)
  • Description
    productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
  • Advisory
    In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Additional description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
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  • Gene target
    ST2  
  • Gene symbol
    CHST9, IL1RL1
  • Short name
    Anti-MOUSE ST2 (N-TERMINAL)
  • Technique
    anti-, Mouse, anti, antibody to, antibodies, mouses
  • Host
    mouse
  • Species
    Mouse, Mouses
  • Alternative name
    Antibody toMOUSE ST2 (N-TERMINAL)
  • Alternative technique
    murine, antibodies
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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