-
Alternative name1
Anti-RABBIT ANTI HUMAN WNT-3a
-
Alternative name2
RABBIT ANTI HUMAN WNT-3a
-
Alternative name3
Lapin ANTI Homo sapiens WNT-3a
-
Alternative name4
WNT-3a
-
Alternative name5
N/A
-
Other names
protein Wnt-3a; Protein Wnt-3a; protein Wnt-3a; wingless-type MMTV integration site family, member 3A; N/A
-
Gene name
WNT-3a
-
Gene name synonims
N/A
-
Other gene names
WNT3A; WNT3A; N/A; N/A
-
Category
Antibodies
-
Clonality
Polyclonal
-
Immunoglobulin isotype
Polyclonal IgG
-
Clone
Polyclonal antibody
-
Host organism
Rabbit
-
Species reactivity
Human
-
Specificity and cross reactivity
WNT-3a This item specifically recognises human WNT-3a, a secreted protein and member of the Wnt family of signalling proteins, which acts as a ligand for members of the frizzled family of seven transmembrane receptors, and plays key roles in many developmental and cell fate decisions, including embryonic patterning, CNS development, and cytoskeletal formation. Wnt-3a acts as a promoter of the proliferation of ventral midbrain dopaminergic neuron precursor cells, and has been implicated in the progressive differentiation of anterior neural cells, as well as regulating the survival and expansion of neural progenitors derived from human embryonic stem cells. Wnt3a has been shown to act upstream of the Notch signalling pathway, in the regulation of somitogenesis, which is believed to be controlled by a segmentation clock, consisting of molecular oscillators in the Notch, Wnt3a and Fgf8 pathways.
-
Purification method
N/A
-
Form Appearance
Purified (Purified IgG - lyophilised)
-
Concentration
IgG concentration 1.0mg/ml after reconstitution
-
Storage and shipping
Prior to reconstitution store at +Store productone at +4 degrees Celsius.. After reconstitution For optimal long term storage, productone should be kept at -20 degrees Celsius. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
-
Tested for
Immunohistology - Paraffin (IHC), Western Blot (WB), ELISA (EIA)
-
Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
-
Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
-
Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Test
MBS Polyclonals supplies antibodies that are for research of human proteins.
-
French translation
anticorps
