-
Alternative name1
Anti-Rabbit Polyclonal to Human KDM1A / LSD1
-
Alternative name2
Rabbit PAb to Human KDM1A / LSD1
-
Alternative name3
Lapin Polyclonal to Homo sapiens KDM1A / LSD1
-
Alternative name4
KDM1A / LSD1
-
Alternative name5
Anti-KDM1A / LSD1 Antibody (N-Terminus) IHC-plus; KDM1A; BHC110; KDM1; LSD1; AOF2; KIAA0601; Human KDM1A; LSD1
-
Other names
lysine-specific histone demethylase 1A isoform b; Lysine-specific histone demethylase 1A; lysine-specific histone demethylase 1A; lysine (K)-specific demethylase 1; BRAF35-HDAC complex protein BHC110; amine oxidase (flavin containing) domain 2; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; lysine (K)-specific demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2
-
Gene name
KDM1A
-
Gene name synonims
LSD1
-
Other gene names
KDM1A; KDM1A; AOF2; KDM1; LSD1; BHC110; AOF2; KDM1; KIAA0601; LSD1
-
Category
Antibodies
-
Clonality
Polyclonal
-
Immunoglobulin isotype
N/A
-
Clone
Polyclonal antibody
-
Host organism
Rabbit
-
Species reactivity
Human, Mouse, Rat
-
Specificity and cross reactivity
17 amino acid peptide from near the amino terminus of human LSD1
-
Purification method
Immunoaffinity Purified
-
Form Appearance
PBS, 0.02% sodium azide.
-
Concentration
1 miligram per 1 mililiter
-
Storage and shipping
Short term Store productone at +4 degrees Celsius., long term aliquot and store productone should be stored at -20 degrees Celsius., avoid freeze thaw cycles. Store undiluted.
-
Tested for
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
-
Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
-
Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
-
Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Test
MBS Polyclonals supplies antibodies that are for research of human proteins.
-
Gene
Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
-
French translation
anticorps
