-
Alternative name1
Anti-RABBIT ANTI HUMAN CD137L:Biotin
-
Alternative name2
RABBIT ANTI HUMAN CD137L:Biotin
-
Alternative name3
Lapin ANTI Homo sapiens CD137L:Biotin
-
Alternative name4
CD137L
-
Alternative name5
N/A
-
Other names
tumor necrosis factor ligand superfamily member 9; Tumor necrosis factor ligand superfamily member 9; tumor necrosis factor ligand superfamily member 9; 4-1BBL; 4-1BB ligand; receptor 4-1BB ligand; homolog of mouse 4-1BB-L; tumor necrosis factor (ligand) superfamily, member 9; 4-1BB ligand
-
Gene name
CD137L
-
Gene name synonims
N/A
-
Other gene names
TNFSF9; TNFSF9; CD137L; 4-1BB-L; 4-1BBL
-
Category
Antibodies
-
Clonality
Polyclonal
-
Immunoglobulin isotype
Polyclonal IgG
-
Clone
Polyclonal antibody
-
Host organism
Rabbit
-
Species reactivity
Human
-
Specificity and cross reactivity
CD137L This item specifically recognise human CD137L, otherwise known as TNFSF9 or 4-1BBL, a type II transmembrane glycoprotein and member of the TNF superfamily, preferentially expressed by B cells, which acts as a ligand for CD137 (4-1BB ligand receptor/TNFRSF9). _x000D__x000D_Interaction between CD137L and its receptor acts as a co-stimulatory signal for T cell activation and expansion, and is involved in the generation of cytotoxic T cells (Tc) and in the process of antigen presentation. Expression of CD137L by a variety of carcinoma cells, suggests a role for CD137L in tumour cell-T cell interactions. _x000D__x000D_
-
Purification method
N/A
-
Form Appearance
Biotin (Purified IgG conjugated to Biotin - lyophilised)
-
Concentration
IgG concentration 0.1 miligram per 1 mililiter after reconstitution
-
Storage and shipping
Prior to reconstitution store at +Store productone at +4 degrees Celsius.. After reconstitution For optimal long term storage, productone should be kept at -20 degrees Celsius. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
-
Tested for
Western Blot (WB), ELISA (EIA)
-
Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
-
Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
-
Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Test
MBS Polyclonals supplies antibodies that are for research of human proteins.
-
Conjugation
Biotinylated
-
French translation
anticorps
