TTF-1/ NKX2.1
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Catalog numberGEN438038
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PricePlease ask
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Size100ug
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Also known asTTF-1/ NKX2.1
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Other nameshomeobox protein Nkx-2.1 isoform 1; Homeobox protein Nkx-2.1; homeobox protein Nkx-2.1; NK-2 homolog A; thyroid nuclear factor 1; thyroid transcription factor 1; homeobox protein NK-2 homolog A; thyroid-specific enhancer-binding protein; NK2 homeobox 1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1; Thyroid-specific enhancer-binding protein; T/EBP
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameNKX2-1
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Gene name synonimsN/A
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Other gene namesNKX2-1; NKX2-1; BCH; BHC; NK-2; TEBP; TTF1; NKX2A; T/EBP; TITF1; TTF-1; NKX2.1; NKX2A; TITF1; TTF1; TTF-1; T/EBP
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1, kappa
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CloneSPM150
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus). Shows a broad species reactivity.; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceN/A
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ConcentrationN/A
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Storage and shippingStore the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
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Gene target
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Gene symbolNKX2-1, NKX2-1-AS1, TTF1, NKX2-2-AS1, RHOH, NKX2-8, NKX2-5, NKX2-4, NKX2-2, NKX2-6
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Short nameTTF-1/ NKX2 1
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Alternative nameAnti-TTF-1/ NKX2.1
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Gene info
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Identity
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Gene
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Long gene nameNK2 homeobox 1
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Synonyms gene
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Synonyms gene name
- benign chorea
- thyroid transcription factor 1
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Synonyms
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Locus
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Discovery year1992-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNKX2-1 antisense RNA 1
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Synonyms gene name
- NKX2-1 antisense RNA 1 (non-protein coding)
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Locus
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Discovery year2011-07-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametranscription termination factor 1
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Synonyms gene name
- transcription termination factor, RNA polymerase I
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GenBank acession
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Locus
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Discovery year1996-05-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Myb/SANT domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNKX2-2 antisense RNA 1
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Synonyms gene name
- NKX2-2 antisense RNA 1 (non-protein coding)
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Synonyms
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Synonyms name
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Locus
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Discovery year2011-07-08
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Pubmed identfication
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameras homolog family member H
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Synonyms gene
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Synonyms gene name
- ras homolog gene family, member H
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-04-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Rho family GTPases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameNK2 homeobox 8
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Synonyms gene
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Synonyms gene name
- NK-2 homolog H (Drosophila)
- NK2 transcription factor related, locus 8 (Drosophila)
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Synonyms
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Locus
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Discovery year2002-07-08
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Entrez gene record
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Pubmed identfication
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNK2 homeobox 5
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Synonyms gene
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Synonyms gene name
- cardiac-specific homeo box
- NK2 transcription factor related, locus 5 (Drosophila)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-02-07
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Pubmed identfication
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameNK2 homeobox 4
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Synonyms gene
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Synonyms gene name
- NK-2 (Drosophila) homolog D
- NK2 transcription factor related, locus 4 (Drosophila)
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Synonyms
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Locus
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Discovery year1992-06-12
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Entrez gene record
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Pubmed identfication
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNK2 homeobox 2
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Synonyms gene
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Synonyms gene name
- NK-2 (Drosophila) homolog B
- NK2 transcription factor related, locus 2 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-06-12
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Entrez gene record
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Pubmed identfication
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNK2 homeobox 6
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Synonyms gene name
- NK2 transcription factor related, locus 6 (Drosophila)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-06-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
