SYVN1 (Synovial Apoptosis Inhibitor 1, E3 Ubiquitin-protein Ligase Synoviolin, DER3, HRD1, KIAA1810)

• Catalog number
  GEN643896
• Price
  Please ask
• Size
  50ug

• Also known as
  SYVN1
• Other names
  Syvn1 protein; N/A; E3 ubiquitin-protein ligase synoviolin; HRD1 protein; synoviolin 1; synovial apoptosis inhibitor 1, synoviolin; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  Syvn1; N/A; RGD1310488; N/A
• Gene name synonims
  Syvn1; N/A; RGD1310488; N/A
• Other gene names
  Syvn1; N/A; RGD1310488; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2b,k
• Clone
  4H4
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human SYVN1.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein A affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB)
• Description
  This 1 is suited for programmed cell-death studies. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  SYVN1   Synovial   Inhibitor   Ubiquitin-protein   Ligase   Synoviolin   DER3   HRD1   KIAA1810  
• Gene symbol
  SYVN1
• Short name
  SYVN1 (Synovial Apoptosis Inhibitor 1, E3 Ubiquitin-protein Ligase Synoviolin, DER3, HRD1, KIAA1810)
• Technique
  apoptosis, apoptosis pathway
• Alternative name
  Anti-SYVN1 (Synovial Apoptosis Inhibitor 1, E3 Ubiquitin-protein Ligase Synoviolin, DER3, HRD1, KIAA1810)
• Alternative technique
  celldeath
• Alternative to gene target
  synovial apoptosis inhibitor 1, synoviolin, SYVN1 and IDBG-56611 and ENSG00000162298 and 102465449,84447, metal ion binding, nuclei, Syvn1 and IDBG-134090 and ENSMUSG00000024807 and 74126, BT.54995 and IDBG-644142 and ENSBTAG00000005076 and 508358

Gene info

• Identity
  HGNC:20738
• Gene
  SYVN1
• Long gene name
  synoviolin 1
• Synonyms gene name
  • synovial apoptosis inhibitor 1, synoviolin
• Synonyms
  • HRD1
  • DER3
• Synonyms name
  • HMG-coA reductase degradation 1 homolog (S. cerevisiae)
• GenBank acession
  • AB085847
• Locus
  11q13.1
• Discovery year
  2004-07-28
• Entrez gene record
  84447
• Pubmed identfication
  • 12975321
• RefSeq identity
  • NM_032431
• Classification
  • MicroRNA protein coding host genes
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000165607

MeSH Data

• Name
  Ligase Chain Reaction
• Concept
  Scope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
• Tree numbers
  • E05.393.620.311
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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