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Also known as
STAT3,
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Other names
signal transducer and activator of transcription 3 isoform 1; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3; DNA-binding protein APRF; acute-phase response factor; signal transducer and activator of transcription 3 (acute-phase response factor); Acute-phase response factor
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
STAT3; STAT3; APRF; HIES; APRF
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Gene name synonims
STAT3; STAT3; APRF; HIES; APRF
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Other gene names
STAT3; STAT3; APRF; HIES; APRF
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG
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Clone
9E559
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Host organism
Rabbit (Oryctolagus cuniculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes phosphorylated human Stat-3 (pY705).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Supernatant
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Form Appearance
Supplied as a liquid in 50 mM Tris- Glycine, pH 7.4, 0.15 M sodium chloride, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
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Tested applications
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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French translation
anticorps
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Gene target
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Gene symbol
STAT3
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Short name
STAT3, phosphorylated, (Tyr705) (Signal Transducer Activator of Transcription 3, Acute-phase Response Factor, APRF) Antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Alternative name
Anti-STAT3, phosphorylated, (Tyr705) (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF)
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Alternative technique
antibodies
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Alternative to gene target
signal transducer and activator of transcription 3 (acute-phase response factor), ADMIO and APRF and HIES, STAT3 and IDBG-50702 and ENSG00000168610 and 6774, protein dimerization activity, nuclei, Stat3 and IDBG-211637 and ENSMUSG00000004040 and 20848, STAT3 and IDBG-640197 and ENSBTAG00000021523 and 101910056,508541
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