SHP 2, phosphorylated (Ser542) (Protein tyrosine phosphatase, non-receptor type 11, SHPTP-2, PTP2C, SH-PTP2, PTP1D, SH-PTP3, Syp, PTPN11)
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Catalog numberGEN631434
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PricePlease ask
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Size100ul
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Also known asSHP 2
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Other namesSHP-2; N/A
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesN/A
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG
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Clone9E544
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Host organismRabbit (Oryctolagus cuniculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human SHP-2 phosphorylated at Tyrosine 542. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodSupernatant
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Form AppearanceSupplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
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Tested applicationsWestern Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolPTPN11, NR0B2, PTPN6, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2
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Short nameSHP 2, phosphorylated (Ser542) (Protein tyrosine phosphatase, non-receptor 11, SHPTP-2, PTP2C, SH-PTP2, PTP1D, SH-PTP3, Syp, PTPN11)
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Alternative nameAnti-SHP 2, phosphorylated (Ser542) (Protein tyrosine phosphatase, non-receptor type 11, SHPTP-2, PTP2C, SH-PTP2, PTP1D, SH-PTP3, Syp, PTPN11)
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Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase non-receptor type 11
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Synonyms gene
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Synonyms gene name
- Noonan syndrome 1
- protein tyrosine phosphatase, non-receptor type 11
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-03-03
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Entrez gene record
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Pubmed identfication
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Classification
- Protein tyrosine phosphatases non-receptor type
- SH2 domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namenuclear receptor subfamily 0 group B member 2
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Synonyms gene name
- nuclear receptor subfamily 0, group B, member 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-08-19
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Entrez gene record
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Pubmed identfication
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Classification
- Nuclear receptor subfamily 0 group B
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase non-receptor type 6
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Synonyms
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Locus
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Discovery year1992-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein tyrosine phosphatases non-receptor type
- SH2 domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 7-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR7 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 329-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-11
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR329 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 512-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 521-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR515 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 509-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namekeratin associated protein 13-2
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Synonyms
-
GenBank acession
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Locus
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Discovery year2003-02-21
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Entrez gene record
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Pubmed identfication
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Classification
- Keratin associated proteins
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VEGA ID