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Also known as
Shc
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Other names
SHC-transforming protein 1 isoform 2; SHC-transforming protein 1; SHC-transforming protein 1; SH2 domain protein C1; SHC-transforming protein 3; SHC-transforming protein A; SHC (Src homology 2 domain-containing) transforming protein 1; SHC (Src homology 2 domain containing) transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
SHC1; SHC1; SHC; SHCA; SHC; SHCA; SH2 domain protein C1
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Gene name synonims
SHC1; SHC1; SHC; SHCA; SHC; SHCA; SH2 domain protein C1
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Other gene names
SHC1; SHC1; SHC; SHCA; SHC; SHCA; SH2 domain protein C1
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
6D761
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Host organism
Mouse (Mus musculus)
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Species reactivity
Canine, Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes human, mouse, rat and canine shc phosphorylated at Tyr239/240. Does not crossreact with non-phosphorylated shc. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Purified by thiophilic adsorption and size exclusion chromatography.
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Form Appearance
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide, PEG, sucrose.
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Concentration
0.1 miligram per 1 mililiter
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50?, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested applications
ELISA (EL/EIA), Western Blot (WB)
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Gene
Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )
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Gene target
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Gene symbol
SHC1, SHC3
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Short name
Shc, phosphorylated (Tyr239, Tyr240) (SHC1, Src homology collagen, Src homology 2, FLJ26504, p52SHC, p66SHC, SH2 domain protein C1, SHC, SHCA, SHC transforming protein 1)
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Alternative name
Anti-Shc, phosphorylated (Tyr239, Tyr240) (SHC1, Src homology and collagen, Src homology 2, FLJ26504, p52SHC, p66SHC, SH2 domain protein C1, SHC, SHCA, SHC transforming protein 1)
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Alternative to gene target
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), ASV and c-SRC and p60-Src and SRC1, SRC and IDBG-74081 and ENSG00000197122 and 6714, transferase activity, nuclei, Src and IDBG-211273 and ENSMUSG00000027646 and 20779, BT.61976 and IDBG-642561 and ENSBTAG00000008938 and 535742
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