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Also known as
Ryanodine Receptor 1,2
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Other names
ryanodine receptor 1; Type 1-like ryanodine receptor; ryanodine receptor 1; ryanodine receptor type1; central core disease of muscle; type 1-like ryanodine receptor; skeletal muscle ryanodine receptor; skeletal muscle calcium release channel; sarcoplasmic reticulum calcium release channel; ryanodine receptor 1 (skeletal); N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
RYR1; N/A; CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; N/A
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Gene name synonims
RYR1; N/A; CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; N/A
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Other gene names
RYR1; N/A; CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
8.BI.500
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Host organism
Mouse (Mus musculus)
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Source organism
Chicken
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Species reactivity
Bovine, Canine, Chicken, Frog, Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Sheep; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes 565kD RyR-1 and RyR-2 in bovine, canine, human, mouse, rat and sheep. Crossreacts with chicken RyRa, RyRb and cardiac isoforms and frog RyRa and RyRb isoforms.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Ascites Neat ascites
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Form Appearance
Supplied as a liquid with 0.05% sodium azide.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
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Tested applications
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translation
anticorps
