Rat Monoclonal [clone 12] (IgG2a) to Bovine Myelin Basic Protein / MBP Antibody

• Catalog number
  GEN245954
• Price
  Please ask
• Size
  0.125 ml

• Also known as
  Myelin Basic Protein / MBP
• Other names
  myelin basic protein isoform 2; Myelin basic protein; Golli-MBP; myelin basic protein; myelin A1 protein; myelin membrane encephalitogenic protein; myelin basic protein; Myelin A1 protein; Myelin membrane encephalitogenic protein
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  MBP
• Gene name synonims
  N/A
• Other gene names
  MBP; MBP; N/A; MBP
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a
• Clone
  12
• Host organism
  Rat (Rattus norvegicus)
• Species reactivity
  Bovine, Chicken, Guinea pig, Human (Homo sapiens), Mammal, Mouse (Mus musculus), Pig, Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Sheep; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Reacts with myelin basic protein from a wide range of species. The Reacts weakly with peptides ending in the Phe 91 where the 91-92 Phe-Phe bond is broken. Synthetic peptide Reacts very well, as does intact MBP. Further epitope analysis indicates binding to a region defined by amino acids 82-87 (DENPVV). Clone 12 has been reported as being suitable for use in Western blotting; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  Tissue culture supernatant, 0.1M Tris, 0.1% sodium azide
• Concentration
  N/A
• Storage and shipping
  For short term storage keep the antibody at +4 degrees Celsius. For longer storage the antibody should be kept at -20 degrees Celsius. Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity.
• Tested applications
  Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA), Radioimmunoassay (RIA)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• French translation
  anticorps

• Gene target
  Monoclonal   12]   IgG2a   Myelin   Protein   MBP  
• Gene symbol
  MBP, PRG2, ENO1, HIVEP2, HIVEP1, PIRC55, PIRC54, PIRC53, PIRC57, PIRC56, SNORD116-12, IGHV3OR16-12, SNORD114-12, SNORD115-12
• Short name
  Monoclonal [clone 12] (IgG2a) Myelin Protein / MBP Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Rat
• Isotype
  IgG2a
• Label
  mbp
• Species
  Bovine, Bos Taurus genes are available form the Bovine Genome database. Rats
• Alternative name
  Anti-Rat Monoclonal [clone 12] (IgG2a) to Bovine Myelin Basic Protein / MBP
• Alternative technique
  antibodies
• Clone name
  12

Gene info

• Identity
  HGNC:6925
• Gene
  MBP
• Long gene name
  myelin basic protein
• Locus
  18q23
• Discovery year
  1986-01-01
• Entrez gene record
  4155
• Pubmed identfication
  • 2425357
• RefSeq identity
  • NM_001025081
• VEGA ID
  OTTHUMG00000132874

Gene info

• Identity
  HGNC:9362
• Gene
  PRG2
• Long gene name
  proteoglycan 2, pro eosinophil major basic protein
• Synonyms gene name
  • proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
• Synonyms
  • MBP
  • BMPG
  • proMBP
• Synonyms name
  • eosinophil major basic protein
• GenBank acession
  • BC005929
• Locus
  11q12.1
• Discovery year
  1993-09-29
• Entrez gene record
  5553
• Pubmed identfication
  • 1565101
• RefSeq identity
  • NM_002728
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000167027

Gene info

• Identity
  HGNC:3350
• Gene
  ENO1
• Long gene name
  enolase 1
• Synonyms gene
  • ENO1L1
  • MPB1
• Synonyms gene name
  • enolase 1, (alpha)
• Synonyms
  • PPH
  • MBP-1
• Synonyms name
  • alpha-enolase
• GenBank acession
  • BC022545
• Locus
  1p36.23
• Discovery year
  1989-04-21
• Entrez gene record
  2023
• Pubmed identfication
  • 9653645
  • 9691177
• RefSeq identity
  • NM_001428
• Classification
  • Enolases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000001773
• Locus Specific Databases
  • LRG_1165

Gene info

• Identity
  HGNC:4921
• Gene
  HIVEP2
• Long gene name
  HIVEP zinc finger 2
• Synonyms gene name
  • human immunodeficiency virus type I enhancer-binding protein 2
  • human immunodeficiency virus type I enhancer binding protein 2
• Synonyms
  • MBP-2
  • HIV-EP2
  • MIBP1
  • ZAS2
  • Schnurri-2
  • ZNF40B
• Synonyms name
  • c-myc intron binding protein 1
• GenBank acession
  • M60119
• Locus
  6q24.2
• Discovery year
  1992-10-21
• Entrez gene record
  3097
• Pubmed identfication
  • 1733857
  • 2022670
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000015713

Gene info

• Identity
  HGNC:4920
• Gene
  HIVEP1
• Long gene name
  HIVEP zinc finger 1
• Synonyms gene
  • ZNF40
• Synonyms gene name
  • human immunodeficiency virus type I enhancer-binding protein 1
  • zinc finger protein 40
  • human immunodeficiency virus type I enhancer binding protein 1
• Synonyms
  • CIRIP
  • MBP-1
  • CRYBP1
  • PRDII-BF1
  • ZAS1
  • Schnurri-1
  • ZNF40A
• GenBank acession
  • J05011
• Locus
  6p24.1
• Discovery year
  1990-10-04
• Entrez gene record
  3096
• Pubmed identfication
  • 2108316
  • 2037300
  • 2504707
• RefSeq identity
  • NM_002114
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000014265

Gene info

• Identity
  HGNC:37559
• Gene
  PIRC55
• Long gene name
  piwi-interacting RNA cluster 55
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313792
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37558
• Gene
  PIRC54
• Long gene name
  piwi-interacting RNA cluster 54
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313815
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37557
• Gene
  PIRC53
• Long gene name
  piwi-interacting RNA cluster 53
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313861
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37561
• Gene
  PIRC57
• Long gene name
  piwi-interacting RNA cluster 57
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313930
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37560
• Gene
  PIRC56
• Long gene name
  piwi-interacting RNA cluster 56
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313862
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33078
• Gene
  SNORD116-12
• Long gene name
  small nucleolar RNA, C/D box 116-12
• Synonyms
  • HBII-85-12
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033424
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003327
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5636
• Gene
  IGHV3OR16-12
• Long gene name
  immunoglobulin heavy variable 3/OR16-12 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 3/OR16-12
• Synonyms
  • IGHV3/OR16-12
• GenBank acession
  • Z29609
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  28304
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000176355

Gene info

• Identity
  HGNC:33000
• Gene
  SNORD114-12
• Long gene name
  small nucleolar RNA, C/D box 114-12
• Synonyms
  • 14q(II-12)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767590
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003205.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33031
• Gene
  SNORD115-12
• Long gene name
  small nucleolar RNA, C/D box 115-12
• Synonyms
  • HBII-52-12
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033449
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003304.1
• Classification
  • Small nucleolar RNAs, C/D box

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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