RAT ANTI MOUSE Gr-1 Antibody

• Catalog number
  GEN212759
• Price
  Please ask
• Size
  100ug

• Also known as
  Gr-1
• Other names
  Lymphocyte antigen 6G; Lymphocyte antigen 6G; N/A; N/A; Ly-6G.1
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  Gr-1
• Gene name synonims
  N/A
• Other gene names
  N/A; Ly6g; N/A; Ly-6G
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2b
• Clone
  RB6-8C5
• Host organism
  Rat (Rattus norvegicus)
• Species reactivity
  Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Gr-1 This item recognises the mouse Gr-1 antigen, a 21-25kD cell surface protein that belongs to the Ly-6 family of proteins. Clone RB6-8C5 reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been demonstrated. The Gr-1 antigen is primarily a marker of myeloid differentiation. In the bone marrow the level of Gr-1 expression is low on immature myeloblasts and increases as the myeloid cells mature to granulocytes. Gr-1 is also expressed on macrophages and transiently on differentiating monocytes. Expression of Gr-1 on a subpopulation of lymphocytes has also been reported. Clone RB6-8C5 has been reported to deplete mouse mature neutrophils in vivo; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  Purified (Purified IgG - liquid)
• Concentration
  IgG concentration 1.0 mg/ml
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
• Tested applications
  Western Blot (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistology - Frozen (IHC)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This is against a protein of mus musculus directed antibody.
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• French translation
  anticorps

• Gene target
  Gr-1  
• Gene symbol
  NR3C1
• Short name
  ANTI MOUSE Gr-1 Antibody
• Technique
  anti mouse, Antibody, Mouse, anti, antibody to, anti mouse antibodies, antibodies against human proteins, antibodies for, mouses
• Host
  Rat
• Species
  Mouse, Mouses, Rats
• Alternative name
  Anti-RAT ANTI MOUSE Gr-1
• Alternative technique
  antibodies, murine

Gene info

• Identity
  HGNC:7978
• Gene
  NR3C1
• Long gene name
  nuclear receptor subfamily 3 group C member 1
• Synonyms gene
  • GRL
• Synonyms gene name
  • nuclear receptor subfamily 3, group C, member 1
  • nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
• Synonyms
  • GR
• Synonyms name
  • glucocorticoid receptor
• GenBank acession
  • X03225
• Locus
  5q31.3
• Discovery year
  2001-06-22
• Entrez gene record
  2908
• Pubmed identfication
  • 2867473
• Classification
  • Nuclear receptor subfamily 3 group C
• VEGA ID
  OTTHUMG00000129677

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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