PBX4 (Pre-B-cell Leukemia Transcription Factor 4, Homeobox Protein PBX4)

• Catalog number
  GEN645786
• Price
  Please ask
• Size
  100ug

• Also known as
  PBX4
• Other names
  pre-B-cell leukemia transcription factor 4; Pre-B-cell leukemia transcription factor 4; pre-B-cell leukemia transcription factor 4; homeobox protein PBX4; pre-B-cell leukemia homeobox 4; Homeobox protein PBX4
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  PBX4; PBX4; N/A; N/A
• Gene name synonims
  PBX4; PBX4; N/A; N/A
• Other gene names
  PBX4; PBX4; N/A; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1,k
• Clone
  1D8
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human PBX4.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein A affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB)
• Description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  PBX4   Pre-B   Leukemia   Transcription   Factor   Homeobox   Protein   PBX4  
• Gene symbol
  PBX4
• Short name
  PBX4 (Pre-B- Leukemia Transcription Factor 4, Homeobox Protein PBX4)
• Alternative name
  Anti-PBX4 (Pre-B-cell Leukemia Transcription Factor 4, Homeobox Protein PBX4)
• Alternative to gene target
  pre-B-cell leukemia homeobox 4, PBX4 and IDBG-40027 and ENSG00000105717 and 80714, sequence-specific DNA binding, nuclei, Pbx4 and IDBG-160818 and ENSMUSG00000031860 and 80720, PBX4 and IDBG-641300 and ENSBTAG00000009975 and 519770
• Tissue
  cell
• Virus
  leukemia

Gene info

• Identity
  HGNC:13403
• Gene
  PBX4
• Long gene name
  PBX homeobox 4
• Synonyms gene name
  • pre-B-cell leukemia transcription factor 4
  • pre-B-cell leukemia homeobox 4
• GenBank acession
  • AJ300182
• Locus
  19p13.11
• Discovery year
  2001-03-14
• Entrez gene record
  80714
• Classification
  • TALE class homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000172310

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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