Paired Immunoglobulin-like Receptor B (PIR-B)

• Catalog number
  GEN601864
• Price
  Please ask
• Size
  100ug

• Also known as
  Paired Immunoglobulin-like Receptor B
• Other names
  paired immunoglobulin-like type 2 receptor alpha isoform 1; Paired immunoglobulin-like type 2 receptor alpha; paired immunoglobulin-like type 2 receptor alpha; cell surface receptor FDF03; inhibitory receptor PILR-alpha; paired immunoglobin-like type 2 receptor alpha; Cell surface receptor FDF03; Inhibitory receptor PILR-alpha
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  PILRA; PILRA; FDF03; N/A
• Gene name synonims
  PILRA; PILRA; FDF03; N/A
• Other gene names
  PILRA; PILRA; FDF03; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a
• Clone
  7H89
• Host organism
  Rat (Rattus norvegicus)
• Source organism
  Mouse (Mus musculus)
• Species reactivity
  Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes mouse Paired Immunoglobulin-like Receptor B (PIR-B). Does not crossreact with mouse PIR-A.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a lyophilized powder from PBS, 5% trehalose.
• Concentration
  N/A
• Storage and shipping
  Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
• Tested applications
  ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Paired   Immunoglobulin-like   Receptor   PIR-B  
• Gene symbol
  LILRB3, LILRB1, PIR, SNRPB, ORM2, ERAL1, OR1B1, SPIB, EXPH5, HLA-B
• Short name
  Paired Immunoglobulin-like Receptor B (PIR-B)
• Alternative name
  Anti-Paired Immunoglobulin-like Receptor B (PIR-B)

Gene info

• Identity
  HGNC:6607
• Gene
  LILRB3
• Long gene name
  leukocyte immunoglobulin like receptor B3
• Synonyms gene name
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
• Synonyms
  • LIR-3
  • HL9
  • ILT5
  • LIR3
  • CD85a
  • PIRB
  • PIR-B
• Synonyms name
  • leucocyte Ig-like receptor B3
• GenBank acession
  • U91928
• Locus
  19q13.42
• Discovery year
  2000-01-11
• Entrez gene record
  11025
• Pubmed identfication
  • 9278324
  • 9382880
• RefSeq identity
  • NM_006864
• Classification
  • CD molecules
  • Inhibitory leukocyte immunoglobulin like receptors
• VEGA ID
  OTTHUMG00000066626

Gene info

• Identity
  HGNC:6605
• Gene
  LILRB1
• Long gene name
  leukocyte immunoglobulin like receptor B1
• Synonyms gene name
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
• Synonyms
  • LIR-1
  • ILT2
  • MIR-7
  • CD85
  • LIR1
  • CD85j
  • PIRB
  • PIR-B
• Synonyms name
  • myeloid inhibitory receptor 7
  • leucocyte Ig-like receptor B1
• GenBank acession
  • AF009220
• Locus
  19q13.42
• Discovery year
  2000-01-11
• Entrez gene record
  10859
• Pubmed identfication
  • 9285411
  • 9382880
• Classification
  • CD molecules
  • Inhibitory leukocyte immunoglobulin like receptors
• VEGA ID
  OTTHUMG00000065695

Gene info

• Identity
  HGNC:30048
• Gene
  PIR
• Long gene name
  pirin
• Synonyms gene name
  • pirin (iron-binding nuclear protein)
• GenBank acession
  • Y07868
• Locus
  Xp22.2
• Discovery year
  2004-06-23
• Entrez gene record
  8544
• Pubmed identfication
  • 9079676
• RefSeq identity
  • NM_003662
• VEGA ID
  OTTHUMG00000021176
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:11153
• Gene
  SNRPB
• Long gene name
  small nuclear ribonucleoprotein polypeptides B and B1
• Synonyms gene
  • SNRPB1
• Synonyms
  • COD
  • SmB/SmB'
  • Sm-B/B'
  • snRNP-B
• Locus
  20p13
• Discovery year
  1988-11-28
• Entrez gene record
  6628
• Pubmed identfication
  • 1376292
• Classification
  • Small nucleolar RNA protein coding host genes
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000031694

Gene info

• Identity
  HGNC:8499
• Gene
  ORM2
• Long gene name
  orosomucoid 2
• Synonyms
  • AGP-B
  • AGP-B'
  • AGP2
• Synonyms name
  • alpha-1-acid glycoprotein, type 2
• Locus
  9q32
• Discovery year
  1991-03-11
• Entrez gene record
  5005
• Pubmed identfication
  • 4711474
  • 2970990
• RefSeq identity
  • NM_000608
• Classification
  • Lipocalins
• VEGA ID
  OTTHUMG00000021014

Gene info

• Identity
  HGNC:3424
• Gene
  ERAL1
• Long gene name
  Era like 12S mitochondrial rRNA chaperone 1
• Synonyms gene name
  • Era (E. coli G-protein homolog)-like 1
  • Era G-protein-like 1 (E. coli)
  • Era-like 12S mitochondrial rRNA chaperone 1
• Synonyms
  • HERA-B
• GenBank acession
  • AF082657
• Locus
  17q11.2
• Discovery year
  1999-11-19
• Entrez gene record
  26284
• Pubmed identfication
  • 10945472
  • 20604745
• VEGA ID
  OTTHUMG00000132675

Gene info

• Identity
  HGNC:8181
• Gene
  OR1B1
• Long gene name
  olfactory receptor family 1 subfamily B member 1
• Synonyms gene name
  • olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
  • olfactory receptor family 1 subfamily B member 1 (gene/pseudogene)
• Synonyms
  • OR9-B
• GenBank acession
  • AC006313
• Locus
  9q33.2
• Discovery year
  1999-12-09
• Entrez gene record
  347169
• RefSeq identity
  • NM_001004450
• Classification
  • Olfactory receptors, family 1
• VEGA ID
  OTTHUMG00000020616

Gene info

• Identity
  HGNC:11242
• Gene
  SPIB
• Long gene name
  Spi-B transcription factor
• Synonyms gene name
  • Spi-B transcription factor (Spi-1/PU.1 related)
• Synonyms
  • SPI-B
• Locus
  19q13.33
• Discovery year
  1994-12-15
• Entrez gene record
  6689
• Pubmed identfication
  • 1406622
• RefSeq identity
  • NM_003121
• Classification
  • ETS transcription factor family
• VEGA ID
  OTTHUMG00000183039

Gene info

• Identity
  HGNC:30578
• Gene
  EXPH5
• Long gene name
  exophilin 5
• Synonyms
  • SLAC2-B
• Synonyms name
  • synaptotagmin-like homologue lacking C2 domains b
• Locus
  11q22.3
• Discovery year
  2005-10-04
• Entrez gene record
  23086
• Pubmed identfication
  • 9734811
  • 11773082
• RefSeq identity
  • NM_015065
• VEGA ID
  OTTHUMG00000166536

Gene info

• Identity
  HGNC:4932
• Gene
  HLA-B
• Long gene name
  major histocompatibility complex, class I, B
• Synonyms gene
  • AS
• Synonyms gene name
  • ankylosing spondylitis
• GenBank acession
  • M15470
• Locus
  6p21.33
• Discovery year
  2001-06-22
• Entrez gene record
  3106
• Pubmed identfication
  • 3459708
• RefSeq identity
  • NM_005514
• Classification
  • C1-set domain containing
  • Histocompatibility complex
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000031153
• Locus Specific Databases
  • IMGT/HLA Database

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